Evidence map›Paper›PMID 34191075›Full record

ReviewAbdominal radiology (New York)2022

Dual-energy CT of acute bowel ischemia.

Markus M Obmann, Gopal Punjabi, Verena C Obmann, Daniel T Boll, Tobias Heye, Matthias R Benz, Benjamin M Yeh

Abstract readReview
PubMed Publisher
In one paragraph

Review in Abdominal radiology (New York), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Computed Tomography Imaging of Acute Mesenteric Ischemia for Interventional Radiology.Interventional radiology (Higashimatsuyama-shi (Japan) · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Dual-Energy CT in Oncologic Imaging.Tomography (Ann Arbor, Mich.) · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Markus M ObmannClinic of Radiology and Nuclear Imaging, University Hospital Basel, Petersgraben 4, 4051, Basel, Switzerland. markusobmann@gmail.com.ORCID http://orcid.org/0000-0001-6586-0034
Gopal PunjabiHennepin Healthcare, Department of Radiology, Minneapolis, USA.
Verena C ObmannDepartment of Diagnostic, Interventional and Pediatric Radiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Daniel T BollClinic of Radiology and Nuclear Imaging, University Hospital Basel, Petersgraben 4, 4051, Basel, Switzerland.
Tobias HeyeClinic of Radiology and Nuclear Imaging, University Hospital Basel, Petersgraben 4, 4051, Basel, Switzerland.
Matthias R BenzClinic of Radiology and Nuclear Imaging, University Hospital Basel, Petersgraben 4, 4051, Basel, Switzerland.
Benjamin M YehDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, USA.
University Hospital of Basel · CHUniversity of California, San Francisco · USHennepin Healthcare Research Institute · USUniversity of Bern · CHUniversity of California, Los Angeles · US

Funding

Preclinical Efficacy of Silicon-based Dual Energy CT Contrast MaterialR41DK104580 · NIDDK · NEXTRAST, INC. · PI BRADLEY, WILLIAM GUERIN · 2014 to 2014
$233k
NIDDK NIH HHS R41 DK104580
6 · The paper itself

Abstract

Acute bowel ischemia is a condition with high mortality and requires rapid intervention to avoid catastrophic outcomes. Swift and accurate imaging diagnosis is essential because clinical findings are commonly nonspecific. Conventional contrast enhanced CT of the abdomen has been the imaging modality of choice to evaluate suspected acute bowel ischemia. However, subtlety of image findings and lack of non-contrast or arterial phase images can make correct diagnosis challenging. Dual-energy CT provides valuable information toward assessing bowel ischemia. Dual-energy CT exploits the differential X-ray attenuation at two different photon energy levels to characterize the composition of tissues and reveal the presence or absence of faint intravenous iodinated contrast to improve reader confidence in detecting subtle bowel wall enhancement. With the same underlying technique, virtual non-contrast images can help to show non-enhancing hyperdense hemorrhage of the bowel wall in intravenous contrast-enhanced scans without the need to acquire actual non-contrast scans. Dual-energy CT derived low photon energy (keV) virtual monoenergetic images emphasize iodine contrast and provide CT angiography-like images from portal venous phase scans to better evaluate abdominal arterial patency. In Summary, dual-energy CT aids diagnosing acute bowel ischemia in multiple ways, including improving visualization of the bowel wall and mesenteric vasculature, revealing intramural hemorrhage in contrast enhanced scans, or possibly reducing intravenous contrast dose.

Indexed as

IodineIodine CompoundsMesenteric IschemiaContrast MediaHumansIschemiaTomography, X-Ray ComputedContrast MediaIodineIodine Compounds

Identifiers

PMID34191075
OpenAlexW3176964977

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.