ArticleSao Paulo medical journal = Revista paulista de medicina
Prevalence of xerostomia and its association with systemic diseases and medications in the elderly: a cross-sectional study.
Article in Sao Paulo medical journal = Revista paulista de medicina. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- A Systematic Review and Meta-Analysis of the Global Prevalence of Dry Mouth in Older Adults.Gerodontology · 2026Pooled it
- Systematic review and meta-analysis on the prevalence and risk factors of oral frailty among older adults.Frontiers in medicine · 2025Pooled it
- Xerogenic medications and clinical markers of salivary hypofunction.Clinical oral investigations · 2026Article
- Effectiveness of photobiomodulation in the treatment of xerostomia in type II diabetic patients.Odontology · 2026Article
- Development and in vitro evaluation of a xylitol/erythritol carbomer gel for xerostomia relief.Odontology · 2026Article
- Compressed Medicated Chewing Gum with Lysozyme Hydrochloride and Ascorbic Acid for Xerostomia Relief and Oral Health Support: Formulation Development, Optimization,Pharmaceutics · 2026Article
- Efficacy of artificial saliva in preventing oral changes in patients admitted to the ICU: a controlled clinical trial.Clinical oral investigations · 2026Article
- Oral mucosal lesions and oral health-related quality of life (GOHAI) in nursing home residents and community-dwelling older adults in Türkiye: a comparative cross-sectional study.BMC geriatrics · 2026Observational
- Population pharmacokinetic modelling revealed large variability in oromucosal absorption of ΔBritish journal of clinical pharmacology · 2026Article
- Orthonasal bioactive volatiles and their effects on salivation: a pilot study.Clinical oral investigations · 2026Article
- Construction and validation of a risk prediction model for oral frailty in rural hypertensive patients.Frontiers in public health · 2026Article
- Age, Dental State and General Health as Risk Factors for Xerostomia and Hyposalivation.International journal of dentistry · 2026Article
- Prevalence and risk factors of oral frailty in elderly cancer inpatients: A cross-sectional study.Medicine · 2025Article
- Examining the relationship between oral health indicators, obesity, and Xerostomia in older adults.BMC public health · 2025Article
- Poly (hydroxyethyl methacrylate) Saliva-Gel: A Polymer-Based Solution for Xerostomia Treatment.ACS applied polymer materials · 2025Article
- Impact of Systemic Medications on Oral Health: A Cross-Sectional Study Among Geriatric Patients.Cureus · 2025Review
- Cancer treatment-related xerostomia: basics, therapeutics, and future perspectives.European journal of medical research · 2024Review
- Impact of Reduced Saliva Production on Intestinal Integrity and Microbiome Alterations: A Sialoadenectomy Mouse Model Study.International journal of molecular sciences · 2024Article
- Prediction of xerostomia in elderly based on clinical characteristics and salivary flow rate with machine learning.Scientific reports · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDry mouth syndrome or xerostomia is defined as decreased salivary flow or hypofunction of salivary glands. Its origins are multicausal and might be the result of a change in the salivary glands or a systemic imbalance.
objectiveTo ascertain the prevalence of self-reported xerostomia and to identify associated factors. DESIGN AND
settingCross-sectional study on the entire population of 293 elderly people over 60 years of age living in a Brazilian municipality.
methodsData were gathered from a questionnaire that asked about demographic data, chronic diseases and use of continuous medications, and which used the Xerostomia Inventory (XI) to evaluate dry mouth sensation. Our analysis consisted of multivariate regression and estimation of odds ratios (OR) and their respective 95% confidence intervals (CI) in binary logistic regression models.
resultsThe prevalence of self-reported xerostomia was 19.1%. Elderly people with diabetes had higher odds of having self-reported xerostomia (OR: 3.59; 95% CI: 1.48-8.68; P < 0.001) as did those who had chronic diseases and used continuous medication (OR: 2.3; 95% CI: 1.19-4.67; P = 0.009). Elderly people who used continuous medication for the gastrointestinal tract were more likely to have xerostomia (OR: 2.14; 95% CI: 1.03-1.44; P = 0.030).
conclusionsElderly people with diabetes and chronic diseases who were using continuous medication were more likely to have dry mouth. Use of continuous medications for the gastrointestinal tract led to a greater chance of having self-reported xerostomia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.