Evidence map›Paper›PMID 34190382›Full record

ReviewChembiochem : a European journal of chemical biology2021

Core Steps to the Azaphilone Family of Fungal Natural Products.

Katherine Williams, Claudio Greco, Andrew M Bailey, Christine L Willis

Abstract readReview
In one paragraph

Review in Chembiochem : a European journal of chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Naturally Occurring Organohalogen Compounds-A Comprehensive Review.Progress in the chemistry of organic natural products · 2023
    Review
  7. Review
  8. Article
  9. Review
  10. Azaphilone alkaloids: prospective source of natural food pigments.Applied microbiology and biotechnology · 2022
    Review
  11. Core Steps to the Azaphilone Family of Fungal Natural Products.Chembiochem : a European journal of chemical biology · 2021
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katherine WilliamsSchool of Biological Sciences, University of Bristol Life Sciences Building, 24 Tyndall Avenue, Bristol, BS8 1TQ, UK.ORCID 0000-0002-1988-8818
Claudio GrecoDepartment of Molecular Microbiology, John Innes Centre, Norwich, NR4 7UH, UK.ORCID 0000-0003-3067-0999
Andrew M BaileySchool of Biological Sciences, University of Bristol Life Sciences Building, 24 Tyndall Avenue, Bristol, BS8 1TQ, UK.ORCID 0000-0002-7594-3703
Christine L WillisSchool of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK.ORCID 0000-0002-3919-3642

Funding

Medical Research Council MR/N029909/1
6 · The paper itself

Abstract

Azaphilones are a family of polyketide-based fungal natural products that exhibit interesting and useful bioactivities. This minireview explores the literature on various characterised azaphilone biosynthetic pathways, which allows for a proposed consensus scheme for the production of the core azaphilone structure, as well as identifying early diversification steps during azaphilone biosynthesis. A consensus understanding of the core enzymatic steps towards a particular family of fungal natural products can aid in genome-mining experiments. Genome mining for novel fungal natural products is a powerful technique for both exploring chemical space and providing new insights into fungal natural product pathways.

Indexed as

BenzopyransBiological ProductsMolecular StructureMonascusPigments, BiologicalazaphiloneBenzopyransBiological ProductsPigments, Biologicalazaphilonebiosynthesisgenome miningnatural productspathway elucidation

Identifiers

PMID34190382
PMCPMC8596599

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.