Evidence map›Paper›PMID 34190334›Full record

ArticleBiometrics2022

Varying-coefficient regression analysis for pooled biomonitoring.

Dewei Wang, Xichen Mou, Yan Liu

Abstract read
In one paragraph

Article in Biometrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Additive partially linear model for pooled biomonitoring data.Computational statistics & data analysis · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dewei WangDepartment of Statistics, University of South Carolina, Columbia, South Carolina, USA.ORCID 0000-0003-0822-8563
Xichen MouDivision of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Tennessee, USA.
Yan LiuSchool of Community Health Sciences, University of Nevada, Reno, Nevada, USA.

Funding

Flexible biomarker evaluation through a cost-effective data collection mechanismR03AI135614 · NIAID · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI WANG, DEWEI · 2019 to 2020
$147k
NIAID NIH HHS R03 AI135614
6 · The paper itself

Abstract

Human biomonitoring involves measuring the accumulation of contaminants in biological specimens (such as blood or urine) to assess individuals' exposure to environmental contamination. Due to the expensive cost of a single assay, the method of pooling has become increasingly common in environmental studies. The implementation of pooling starts by physically mixing specimens into pools, and then measures pooled specimens for the concentration of contaminants. An important task is to reconstruct individual-level statistical characteristics based on pooled measurements. In this article, we propose to use the varying-coefficient regression model for individual-level biomonitoring and provide methods to estimate the varying coefficients based on different types of pooled data. Asymptotic properties of the estimators are presented. We illustrate our methodology via simulation and with application to pooled biomonitoring of a brominated flame retardant provided by the National Health and Nutrition Examination Survey (NHANES).

Indexed as

Biological MonitoringEnvironmental ExposureComputer SimulationHumansNutrition SurveysRegression Analysishomogeneous poolinglocal linear fitNational Health and Nutrition Examination Surveypooled biospecimensrandom poolingvarying-coefficient models

Identifiers

PMID34190334
PMCPMC8716640

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.