Evidence map›Paper›PMID 34190006›Full record

ArticleTechnology in cancer research & treatment

Can the Risk of Dysphagia in Head and Neck Radiation Therapy Be Predicted by an Automated Transit Fluence Monitoring Process During Treatment? A First Comparative Study of Patient Reported Quality of Life and the Fluence-Based Decision Support Metric.

Seng Boh Lim, Nancy Lee, Kaveh Zakeri, Peter Greer, Todsaporn Fuangrod, Frederick Coffman, Laura Cerviño, D Michael Lovelock

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Seng Boh LimDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0002-4054-8789
Nancy LeeDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Kaveh ZakeriDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Peter GreerCalvary Mater Newcastle Hospital, New South Wales, Australia.
Todsaporn FuangrodHRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy, Bangkok, Thailand.
Frederick CoffmanSchool of Health Professions, Rutgers University, Newark, NJ, USA.
Laura CerviñoDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
D Michael LovelockDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Memorial Sloan Kettering Cancer Center · USCalvary Mater Newcastle Hospital · AUChulabhorn Hospital · THRutgers, The State University of New Jersey · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

PURPOSE/OBJECTIVE(S): The additional personnel and imaging procedures required for Adaptive Radiation Therapy (ART) pose a challenge for a broad implementation. We hypothesize that a change in transit fluence during the treatment course is correlated with the change of quality of life and thus can be used as a replanning trigger. MATERIALS/

methodsTwenty-one head and neck cancer (HNC) patients filled out an MD Anderson Dysphagia Inventory (MDADI) questionnaire, before-and-after the radiotherapy treatment course. The transit fluence was measured by the Watchdog (WD)

resultsNo statistically significant correlation was found for age, gender and ΔW. <D

conclusionA transit fluence based decision support metric (DSM) is statistically correlated with the dysphagia risk. It can not only be used as an early signal in assisting clinicians in the ART patient selection for replanning, but also lowers the resource barrier of ART implementation.

Indexed as

Quality of LifeAdultAgedAged, 80 and overDeglutition DisordersDose Fractionation, RadiationFemaleHead and Neck NeoplasmsHumansMaleMiddle AgedPatient Reported Outcome MeasuresPharyngeal MusclesRadiation DosageRadiotherapy Planning, Computer-AssistedRisk Assessmentadaptive radiation therapydecision support informetricdysphagiahead and neck cancerin-vivo dosimetryxerostomia

Identifiers

PMID34190006
PMCPMC8252347
OpenAlexW3177276510

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.