Evidence map›Paper›PMID 34189971›Full record

ArticleNASN school nurse (Print)2021

Managing Acute Seizures: New Rescue Delivery Option and Resources to Assist School Nurses.

Patricia Dean, Kathryn O'Hara, Lai Brooks, Ruth Shinnar, Genei Bougher, Nancy Santilli

Abstract read
In one paragraph

Article in NASN school nurse (Print), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Patricia DeanEpilepsy Program Specialist, Comprehensive Epilepsy Center, Nicklaus Children's Hospital, Miami, FL.
Kathryn O'HaraClinical Research Nurse, Department of Neurology, Virginia Commonwealth University, Richmond, VA.
Lai BrooksSenior Director of the Neuroscience Institute, Le Bonheur Children's Hospital, Memphis, TN.
Ruth ShinnarConsultant, New Rochelle, NY.
Genei BougherVice President/Subinvestigator, Northwest Florida Clinical Research Group, LLC, Gulf Breeze, FL.
Nancy SantilliGlobal Managing Director, Human Care Systems, Boston, MA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Approximately 470,000 children and adolescents in the United States have epilepsy, 30% of whom experience seizures despite antiseizure drug regimens. School nurses, teachers, caregivers, and parents play integral roles in implementing a care plan that avoids triggers, recognizes signs, and provides supportive care-ideally, guided by a patient-specific seizure action plan, which may include the use of rescue medication. Benzodiazepines are the mainstay of seizure rescue medication; for decades, rectally administered diazepam was the only approved rescue medication for seizure clusters outside the hospital setting. However, rectal administration has limitations that could delay treatment (e.g., social acceptability, removal of clothing, positioning). More recently, intranasal midazolam (for patients ≥12 years) and intranasal diazepam (for patients ≥6 years) were approved for this indication. Training and education regarding newer forms of rescue medication should improve confidence in the ability to treat seizures in school with the goal of increasing the safety of students with epilepsy.

Indexed as

NursesSchool NursingAdolescentAnticonvulsantsChildDiazepamHumansSchoolsSeizuresAnticonvulsantsDiazepambenzodiazepinediazepamepilepsyintranasalmidazolamnasal sprayrescue medicationseizureseizure cluster

Identifiers

PMID34189971
PMCPMC8586177

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.