Evidence map›Paper›PMID 34189844›Full record

ArticleJournal of the International AIDS Society2021

Reductions in HIV incidence are likely to increase the importance of key population programmes for HIV control in sub-Saharan Africa.

Geoff P Garnett

Abstract read
In one paragraph

Article in Journal of the International AIDS Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  9. Preventing HIV in women in Africa.Nature medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Geoff P GarnettTuberculosis and HIV Strategic Team, Bill & Melinda Gates Foundation, Seattle, WA, USA.ORCID 0000-0001-7495-1958

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAn efficient HIV response requires that resources be focussed on effective interventions for those most at risk of acquiring and transmitting infection. As HIV epidemics evolve the distribution of HIV across key and other populations will change. Here, the epidemiological concepts underpinning these changes are described and the importance of appropriate allocation of effective interventions is discussed. DISCUSSION: In many sub-Saharan African countries HIV epidemics have been categorized as "generalized," and HIV testing, treatment and prevention interventions have focussed on the "general" population. As HIV epidemics are better controlled the relative importance of "key" populations will increase, dominating the ongoing burden of disease and providing the potential for repeated outbreaks of HIV if interventions are relaxed. The basic reproductive number (R

conclusionsContinued control of HIV will increasingly rely on resources, programmes and interventions supporting key populations. Current epidemiological and programmatic approaches for key populations in sub-Saharan Africa are insufficient with a need for an improved understanding of local epidemiology and the effectiveness of interventions.

Indexed as

EpidemicsHIV InfectionsAfrica South of the SaharaHumansIncidencePopulation Controlcost-effectivenessepidemic controlHIV epidemiologykey populationsreproductive numberstransmission dynamics

Identifiers

PMID34189844
PMCPMC8242973

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.