Evidence map›Paper›PMID 34189678›Full record

ReviewCurrent hypertension reports2021

Hypertension, Obesity, and COVID-19: a Collision of Pandemics.

Annalisa Perez, Mihran Naljayan, Imran Shuja, Andre Florea, Efrain Reisin

Open access · bronzeAbstract readReview
In one paragraph

Review in Current hypertension reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

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  15. What Is the Impact of Baseline Inflammatory and Hemostatic Indicators with the Risk of Mortality in Severe Inpatients with COVID-19: A Retrospective Study.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Annalisa PerezDepartment of Internal Medicine, Section of Nephrology and Hypertension, Louisiana State University, 1542 Tulane Avenue Suite 330, New Orleans, LA, 70112, USA. apere5@lsuhsc.edu.
Mihran NaljayanDepartment of Internal Medicine, Section of Nephrology and Hypertension, Louisiana State University, 1542 Tulane Avenue Suite 330, New Orleans, LA, 70112, USA.
Imran ShujaDepartment of Internal Medicine, Section of Nephrology and Hypertension, Louisiana State University, 1542 Tulane Avenue Suite 330, New Orleans, LA, 70112, USA.
Andre FloreaDepartment of Internal Medicine, Section of Nephrology and Hypertension, Louisiana State University, 1542 Tulane Avenue Suite 330, New Orleans, LA, 70112, USA.
Efrain ReisinDepartment of Internal Medicine, Section of Nephrology and Hypertension, Louisiana State University, 1542 Tulane Avenue Suite 330, New Orleans, LA, 70112, USA.
Louisiana State University · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

purpose of reviewTo highlight the epidemiology and pathophysiology of hypertension and obesity in COVID-19 infection RECENT

findingsHypertension and obesity have emerged as significant risk factors for contracting the COVID-19 virus and the subsequent severity of illness. ACE2 receptor expression and dysregulation of the RAAS pathway play important roles in the pathophysiology of these associations, as do the pro-inflammatory state and cytokine dysregulation seen in obesity. Some of these patterns have also been seen historically in other viral illnesses. Understanding the mechanisms behind the associations between COVID-19, hypertension, and obesity is important in developing effective targeted therapies and monitoring vaccine response and efficacy. More research is needed to apply our growing knowledge of the pathophysiology of COVID-19, hypertension, and obesity to prevention and treatment. Interventions focusing on lifestyle modification in managing hypertension and obesity can potentially have a positive impact on containing this pandemic and future viral illness outbreaks.

Indexed as

COVID-19HypertensionHumansObesityPandemicsRenin-Angiotensin SystemSARS-CoV-2ACE2 receptorCOVID-19HypertensionObesityRAAS

Identifiers

PMID34189678
PMCPMC8241408
OpenAlexW3176639226

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.