ArticleAnnals of biomedical engineering2021
Balance Between Mechanical Stability and Mechano-Biology of Fracture Healing Under Volar Locking Plate.
Article in Annals of biomedical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Dynamic Fracture Fixation Plates: A Systematic Review of Evolving Design Approaches.Annals of biomedical engineering · 2025Pooled it
- Effect of muscle atrophy on fracture healing: insights from a tibial musculoskeletal-finite element model.Biomechanics and modeling in mechanobiology · 2026Article
- Computational models for predicting bone fracture healing: a review of modeling approaches, predictions, and emerging strategies.Biomechanics and modeling in mechanobiology · 2026Review
- An age-related computational framework for predicting tibial fracture healing under walking rehabilitation: a comparison between younger and older adults.Medical & biological engineering & computing · 2026Article
- Real-time biofeedback monitoring rehabilitation of distal radius fracture.Journal of neuroengineering and rehabilitation · 2025Article
- Retrospective analysis of the use of orthopedic reduction robots in treating low-energy osteoporotic unstable pelvic fractures in the elderly.Journal of orthopaedic surgery and research · 2025Article
- [Application of minimally invasive techniques in clinical treatment of tibial plateau fractures].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Review
- Individual muscle strengths in rehabilitation outcomes of distal radius fracture.Journal of neuroengineering and rehabilitation · 2025Article
- A novel biomimetic trabecular bone metal plate for bone repair and osseointegration.Regenerative biomaterials · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
The application of volar locking plate (VLP) is promising in the treatment of dorsally comminuted and displaced fracture. However, the optimal balance between the mechanical stability of VLP and the mechanobiology at the fracture site is still unclear. The purpose of this study is to develop numerical models in conjunction with experimental studies to identify the favourable mechanical microenvironment for indirect healing, by optimizing VLP configuration and post-operative loadings for different fracture geometries. The simulation results show that the mechanical behaviour of VLP is mainly governed by the axial compression. In addition, the model shows that, under relatively large gap size (i.e., 3-5 mm), the increase of FWL could enhance chondrocyte differentiation while a large BPD could compromise the mechanical stability of VLP. Importantly, bending moment produced by wrist flexion/extension and torsion moment produced from forearm rotation could potentially hinder endochondral ossification at early stage of healing. The developed model could potentially assist orthopaedic surgeons in surgical pre-planning and designing post-operation physical therapy for treatment of distal radius fractures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.