Evidence map›Paper›PMID 34189624›Full record

ArticleArchives of osteoporosis2021

Number of teeth is associated with hip fracture and femoral neck bone mineral density in the NHANES.

Yau-Hua Yu, Wai S Cheung, Donald R Miller, Bjorn Steffensen

Open access · greenAbstract read
In one paragraph

Article in Archives of osteoporosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yau-Hua YuDepartment of Periodontology, Tufts University School of Dental Medicine, One Kneeland Street, Boston, MA, 02111, USA. Yau-Hua.Yu@tufts.edu.
Wai S CheungDepartment of Periodontology, Tufts University School of Dental Medicine, One Kneeland Street, Boston, MA, 02111, USA.
Donald R MillerCenter for Healthcare Organization and Implementation Research, VA Bedford Healthcare System, Bedford, MA, 01730, USA.
Bjorn SteffensenDepartment of Periodontology, Tufts University School of Dental Medicine, One Kneeland Street, Boston, MA, 02111, USA.
Tufts University · USBoston University · US

Funding

Exploring genomic determinants of periodontal disease via shared genetic pathways with cardiovascular disease, diabetes, and bone densityK23DE026804 · NIDCR · TUFTS UNIVERSITY BOSTON · PI YU, YAU-HUA · 2017 to 2021
$685k
NIDCR NIH HHS K23 DE026804NIDCR NIH HHS L30 DE028110
6 · The paper itself

Abstract

PURPOSE/

introductionTooth loss has been found to be associated with fractures and osteoporosis. However, the associations between number of teeth with bone mineral density as well as with hip fractures have not been explored in the same study setting.

methodsData from the cross-sectional National Health and Nutrition Examination Survey (2005-2010, 2013-2014, and 2017-2018) with completed femoral neck bone mineral density (BMD) measurements, osteoporosis questionnaires, and dentition examinations were analyzed. A total of 15,198 participants, with a mean age of 53.9 and diverse ethnicity, males (52%), and females (48%), were analyzed. Multivariate logistic regression analyses for self-reported hip fractures, self-reported osteoporosis, and measured low femoral BMD accounting for traditional risk factors were tested for the total number of natural teeth (NoT) present, or by NoT in the anterior or posterior segments.

resultsSubjects with fewer natural teeth present were more likely to report a hip fracture, osteoporosis, or having lower levels of femoral neck BMD. With one additional tooth present in the mouth, there was a decreased association with self-reported hip fracture [OR(95%CI) = 0.98(0.96-0.99); P = 0.005] or with less likelihood of having low femoral neck BMD [OR(95%CI) = 0.99(0.97-1.00); P = 0.007].

conclusionsWith the limitation of the cross-sectional study design, results should be interpreted cautiously, yet our analyses point to an association between a decreased number of natural teeth present and self-reported hip fractures or low femoral neck BMD. The number of teeth present could be potentially utilized for assessing risks of hip fracture and osteoporosis. Future research is needed to validate our findings.

Indexed as

Femur NeckHip FracturesAbsorptiometry, PhotonBone DensityCross-Sectional StudiesFemaleHumansMaleNutrition SurveysBone mineral densityDentitionFemoral neckHip fracturesOsteoporosisPermanent

Identifiers

PMID34189624
PMCPMC8312725
OpenAlexW3175021738

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.