Evidence map›Paper›PMID 34189606›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021

The effectiveness of an oral health education and prevention program on the incidence and severity of oral mucositis in pediatric cancer patients: a non-randomized controlled study.

Paula Maria Maracajá Bezerra, Maria Eduarda Alves Sampaio, Fabio Gomes Dos Santos, Isabella Lima Arrais Ribeiro, Bianca Marques Santiago, Simone Alves de Sousa, Ana Maria Gondim Valença

Abstract readControlled Clinical Trial
PubMed Publisher
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Guideline
  2. The parents voice on oral health care from two paediatric oncology units.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Observational
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Paula Maria Maracajá BezerraPostgraduate Program in Dentistry, Federal University of Paraíba, Campus - I Cidade Universitária, João Pessoa, PB, 58051-900, Brazil. paulammaracaja@gmail.com.ORCID http://orcid.org/0000-0002-9705-8959
Maria Eduarda Alves SampaioPostgraduate Program in Dentistry, Federal University of Paraíba, Campus - I Cidade Universitária, João Pessoa, PB, 58051-900, Brazil.
Fabio Gomes Dos SantosPostgraduate Program in Dentistry, Federal University of Paraíba, Campus - I Cidade Universitária, João Pessoa, PB, 58051-900, Brazil.
Isabella Lima Arrais RibeiroPostgraduate Program in Dentistry, Federal University of Paraíba, Campus - I Cidade Universitária, João Pessoa, PB, 58051-900, Brazil.
Bianca Marques SantiagoPostgraduate Program in Dentistry, Federal University of Paraíba, Campus - I Cidade Universitária, João Pessoa, PB, 58051-900, Brazil.
Simone Alves de SousaPostgraduate Program in Dentistry, Federal University of Paraíba, Campus - I Cidade Universitária, João Pessoa, PB, 58051-900, Brazil.
Ana Maria Gondim ValençaStatistics Department, Federal University of Paraíba, João Pessoa, PB, Brazil.
Universidade Federal da Paraíba · BR

Funding

Coordination of Superior Level Staff Improvement 1835768
6 · The paper itself

Abstract

purposeTo investigate the effectiveness of an Oral Health Education and Prevention Program (OHEPP) on the incidence and severity of oral mucositis (OM) in pediatric cancer patients. The OHEEP was a ludic strategy for promoting oral health and monitoring the oral health condition.

methodsWe compared the incidence and severity of OM in patients who attended the OHEPP against those under similar conditions who did not receive educational interventions. Both groups were examined for 6 weeks by calibrated examiners (k > 0.8) using the modified Oral Assessment Guide (OAG). A total of 14 patients aged 2 to 18 years were included in each group and matched for sex, age, tumor type, and treatment modality. The incidence and severity of OM were compared using the chi-squared test (α = 5%), and the relative risk and effectiveness of the OHEPP were calculated with a statistical power of 0.97. Differences in total OAG scores between the groups were determined by the Mann-Whitney test (α = 5%).

resultsThere was a higher incidence of OM in patients who did not attend the OHEPP (P = 0.005), and the relative risk of developing OM was significantly lower in OHEPP attendants (RR: 0.73; CI 0.60-0.92). No difference in the occurrence of severe OM was observed. OHEPP reduced the risk of developing OM by 1.4-fold, with an effectiveness of 27%. There was a difference in total OAG scores (P = 0.041).

conclusionParticipation in OHEPP was an effective measure to reduce the incidence of OM in pediatric cancer patients.

Indexed as

NeoplasmsStomatitisChildDouble-Blind MethodHealth EducationHumansIncidenceMucositisOral healthPatient education as topicPediatric dentistry

Identifiers

PMID34189606
OpenAlexW3175149430

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.