ArticleJournal of Alzheimer's disease reports2021
Is There a Characteristic Autonomic Response During Outbursts of Combative Behavior in Dementia Patients?
Article in Journal of Alzheimer's disease reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02617056 (Objective Assessment of Behavioral Associations of Patients With Dementia), which is not on this map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Objective Assessment of Behavioral Associations of Patients With Dementia
Who cites it
8 citing papers in PubMed, 7 citations in OpenAlex.
- Research progress in agitation early warning monitoring and new technologies for critically ill patients: a narrative review.Frontiers in medicine · 2026Review
- Dysautonomia in Alzheimer's Disease: A Systematic Review.Brain sciences · 2025Review
- A New Perspective on Agitation in Alzheimer's Disease: A Potential Paradigm Shift.International journal of molecular sciences · 2025Article
- RadioMe: an automated home-based radio, music playlist, and diary reminder system: Report on recruitment, music compilation, and listening, and preliminary testing of heart rate activated music.Frontiers in psychology · 2025Article
- Evaluating the effectiveness of integrating biofeedback in the treatment of aggressive outbursts (BRET-IA2): A study protocol.PloS one · 2025Article
- Insight of autonomic dysfunction in CLN3 disease: a study on episodes resembling paroxysmal sympathetic hyperactivity (PSH).Orphanet journal of rare diseases · 2024Article
- Wearables measuring electrodermal activity to assess perceived stress in care: a scoping review.Acta neuropsychiatrica · 2023Review
- Treatment of non-epileptic episodes of anxious, fearful behavior in adolescent juvenile neuronal ceroid lipofuscinosis (CLN3 disease).Frontiers in neurology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
We sought to determine whether skin conductance level could warn of outbursts of combative behavior in dementia patients by using a wristband device. Two outbursts were captured and are reported here. Although no physiologic parameter measured by the wristband gave advance warning, there is a common pattern of parasympathetic withdrawal (increased heart rate) followed approximately 30 seconds later by sympathetic activation (increased skin conductance). In the literature, a similar pattern occurs in psychogenic non-epileptic seizures. We hypothesize that similar autonomic responses reflect similarities in pathophysiology and that physical activity may partially account for the time course of skin conductance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.