Evidence map›Paper›PMID 34189239›Full record

ArticleSSM - population health2021

Living alone as a risk factor for cancer incidence, case-fatality and all-cause mortality: A nationwide registry study.

Marko Elovainio, Sonja Lumme, Martti Arffman, Kristiina Manderbacka, Eero Pukkala, Christian Hakulinen

Open access · goldAbstract read
In one paragraph

Article in SSM - population health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Loneliness in prostate cancer survivors.Journal of cancer research and clinical oncology · 2026
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  16. Loneliness as a predictor of mortality in cancer patients, a cohort studyBiomedica : revista del Instituto Nacional de Salud · 2024
    Article
  17. Article
  18. Marital Status, Living Arrangement, and Survival among Individuals with Advanced Prostate Cancer in the International Registry for Men with Advanced Prostate Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Marko ElovainioResearch Program Unit, Faculty of Medicine, University of Helsinki, Finland.
Sonja LummeResearch Program Unit, Faculty of Medicine, University of Helsinki, Finland.
Martti ArffmanDepartment of Health and Social Care Systems, Finnish Institute for Health and Welfare, Helsinki, Finland.
Kristiina ManderbackaDepartment of Health and Social Care Systems, Finnish Institute for Health and Welfare, Helsinki, Finland.
Eero PukkalaFinnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki, Finland.
Christian HakulinenDepartment of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Finland.
University of Helsinki · FIFinnish Institute for Health and Welfare · FITampere University · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lack of social contacts has been associated with an increased risk of cancer mortality, but it is not known whether living alone increases the risk of cancer incidence or case fatality. We examined the association between living alone with cancer incidence, case-fatality and all-cause mortality in eight most common cancers. All patients with their first cancer diagnosis in 2000-2017 were identified from the nationwide Finnish Cancer Registry. Information on living arrangements was derived from Statistics Finland. The incidence analyses were conducted using Poisson regression. The total Finnish population served as the population at risk. Fine-Gray model was used to estimate case-fatality and Cox proportional regression model all-cause mortality. In men, we found an association between history of living alone and excess lung cancer incidence but living alone seemed to be associated with lower incidence of prostate cancer and skin melanoma. In women, living alone was more consistently associated with higher incidence of all studied cancers. Cancer patients living alone had an 11%-80% statistically significantly increased case-fatality and all-cause mortality in all studied cancers in men and in breast, colorectal and lung cancer in women. Living alone is consistently associated with increased cancer incidence risk in women but only in some cancers in men. Both men and women living alone had an increased risk of all-cause mortality after cancer diagnosis.

Indexed as

CancerLonelinessMechanismsPopulationRisk

Identifiers

PMID34189239
PMCPMC8219898
OpenAlexW3167440375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.