Evidence map›Paper›PMID 34189158›Full record

ArticleOpen forum infectious diseases2021

The Dynamics of Infectious Diseases Associated With Injection Drug Use in Lawrence and Lowell, Massachusetts.

Gregg S Gonsalves, A David Paltiel, Thomas Thornhill, Suzan Iloglu, Alfred DeMaria, Kevin Cranston, R Monina Klevens, Rochelle P Walensky, Joshua L Warren

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  6. Review
  7. Article
  8. Patterns of Infectious Disease Associated With Injection Drug Use in Massachusetts.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  9. Article
  10. Article
  11. Study on the Global Stability for a Generalized SEIR Epidemic Model.Computational intelligence and neuroscience · 2022
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Gregg S GonsalvesDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, USA.ORCID https://orcid.org/0000-0002-5789-9841
A David PaltielDepartment of Health Policy and Management, Yale School of Public Health, New Haven, Connecticut, USA.
Thomas ThornhillDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, USA.
Suzan IlogluDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, USA.
Alfred DeMariaBureau of Infectious Disease and Laboratory Sciences, Massachusetts Department of Public Health, Boston, Massachusetts, USA.
Kevin CranstonBureau of Infectious Disease and Laboratory Sciences, Massachusetts Department of Public Health, Boston, Massachusetts, USA.
R Monina KlevensBureau of Infectious Disease and Laboratory Sciences, Massachusetts Department of Public Health, Boston, Massachusetts, USA.
Rochelle P WalenskyMassachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Joshua L WarrenDepartment of Biostatistics, Yale School of Public Health, Connecticut, USA.
Yale University · USMassachusetts Department of Public Health · USHarvard University · USYale New Haven Health System · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Development and application of a new simulation model for COVID-19R01AI042006 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Kenneth Alan Freedberg, Anne Neilan · 1998 to 2026
$12.9M
Making Better Decisions: Policy Modeling for AIDS and Drug AbuseR37DA015612 · NIDA · STANFORD UNIVERSITY · PI DOUGLAS K OWENS · 2019 to 2026
$6.3M
Modeling the impact and cost-effectiveness of next-generation rotavirus vaccine strategies in low- and middle-income countriesR01AI112970 · NIAID · YALE UNIVERSITY · PI PITZER, VIRGINIA E · 2015 to 2024
$4.1M
Predicting and monitoring variations in the effects of vaccines against RSVR01AI137093 · NIAID · YALE UNIVERSITY · PI Virginia E Pitzer, Daniel Martin Weinberger · 2018 to 2026
$3.4M
Novel, Adaptive Approaches to Predicting and Responding to Outbreaks of Overdose, HIV and HCV Among People Who Use DrugsDP2DA049282 · NIDA · YALE UNIVERSITY · PI GONSALVES, GREGG STEVEN · 2019 to 2019
$2.5M
NCATS NIH HHS UL1 TR001863NIAID NIH HHS R01 AI042006NIAID NIH HHS R01 AI112970NIAID NIH HHS R01 AI137093NIDA NIH HHS DP2 DA049282NIDA NIH HHS R37 DA015612
6 · The paper itself

Abstract

backgroundThere are a wide variety of infectious complications of injection drug use. Understanding the trajectory of these complications might inform the development of an early warning system for human immunodeficiency virus (HIV) outbreaks that occur regularly among people who inject drugs (PWID).

methodsA distributed lag Poisson regression model in the Bayesian setting was used to examine temporal patterns in the incidence of injection-associated infectious diseases and their association with HIV cases in Lawrence and Lowell, Massachusetts between 2005 and 2018.

resultsCurrent-month HIV counts are associated with fatal overdoses approximately 8 months prior, cases of infective endocarditis 10 months prior, and cases of skin and soft tissue infections and incision and drainage procedures associated with these infections 12 months prior.

conclusionsCollecting data on these other complications associated with injection drug use by public health departments may be important to consider because these complications may serve as input to a sentinel system to trigger early intervention and avert potential outbreaks of HIV.

Indexed as

endocarditisHIVinjection drug usesoverdoseskin and soft tissue infection

Identifiers

PMID34189158
PMCPMC8231383
OpenAlexW3138206245

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.