Evidence map›Paper›PMID 34189141›Full record

SynthesisBioMed research international2021

Manual Therapy as a Management of Cervical Radiculopathy: A Systematic Review.

Sergio Borrella-Andrés, Isabel Marqués-García, María Orosia Lucha-López, Pablo Fanlo-Mazas, Mar Hernández-Secorún, Albert Pérez-Bellmunt, José Miguel Tricás-Moreno, César Hidalgo-García

2 registry-linked trialsOpen access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05404646 nacompletednot on this mapstarted 2022, after this paper: background citation

Effects of Thoracic Mobility Versus Stretching Exercise Program on Pain, Range of Motion and Function in Patients of Cervical Radiculopathy.

TypeinterventionalSponsorRiphah International UniversityRan2022 to 2023Enrolled44ConditionsCervical RadiculopathyArmsThoracic mobility exercises with conventional physical therapy for cervical radiculopathy, Thoracic stretching exercises with conventional physical therapy for cervical radiculopathy
NCT06397196 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effects of Laser Guided Cervical Proprioceptive Exercises on Pain, Range of Motion, Cervical Position Sense and Functional Disability in Patients With Cervical Radiculopathy

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2024Enrolled52ConditionsCervical RadiculopathyArmsLaser guided proprioceptive exercises, Routine Physical therapy
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Manual physical therapy for neck disorders: an umbrella review.The Journal of manual & manipulative therapy · 2025
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  8. Scapular pain in cervical radiculopathy: A scoping review.North American Spine Society journal · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sergio Borrella-AndrésHealth Sciences Faculty, University of Zaragoza, Zaragoza 50009, Spain.ORCID https://orcid.org/0000-0002-9354-2938
Isabel Marqués-GarcíaHealth Sciences Faculty, University of Zaragoza, Zaragoza 50009, Spain.
María Orosia Lucha-LópezHealth Sciences Faculty, University of Zaragoza, Zaragoza 50009, Spain.
Pablo Fanlo-MazasHealth Sciences Faculty, University of Zaragoza, Zaragoza 50009, Spain.ORCID https://orcid.org/0000-0003-3472-072X
Mar Hernández-SecorúnHealth Sciences Faculty, University of Zaragoza, Zaragoza 50009, Spain.ORCID https://orcid.org/0000-0001-9678-3449
Albert Pérez-BellmuntDepartment of Basic Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallés 08195, Spain.ORCID https://orcid.org/0000-0002-5607-0708
José Miguel Tricás-MorenoHealth Sciences Faculty, University of Zaragoza, Zaragoza 50009, Spain.
César Hidalgo-GarcíaHealth Sciences Faculty, University of Zaragoza, Zaragoza 50009, Spain.
Universidad de Zaragoza · ESUniversitat Internacional de Catalunya · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCervical radiculopathy is defined as a disorder involving dysfunction of the cervical nerve roots characterised by pain radiating and/or loss of motor and sensory function towards the root affected. There is no consensus on a good definition of the term. In addition, the evidence regarding the effectiveness of manual therapy in radiculopathy is contradictory.

objectiveTo assess the effectiveness of manual therapy in improving pain, functional capacity, and range of motion in treating cervical radiculopathy with and without confirmation of altered nerve conduction.

methodsSystematic review of randomised clinical trials on cervical radiculopathy and manual therapy, in PubMed, Web of Science, Scopus, PEDro, and Cochrane Library Plus databases. The PRISMA checklist was followed. Methodological quality was evaluated using the PEDro scale and RoB 2.0. tool.

results17 clinical trials published in the past 10 years were selected. Manual therapy was effective in the treatment of symptoms related to cervical radiculopathy in all studies, regardless of the type of technique and dose applied.

conclusionsThis systematic review did not establish which manual therapy techniques are the most effective for cervical radiculopathy with electrophysiological confirmation of altered nerve conduction. Without this confirmation, the application of manual therapy, regardless of the protocol applied and the manual therapy technique selected, appears to be effective in reducing chronic cervical pain and decreasing the index of cervical disability in cervical radiculopathy in the short term. However, it would be necessary to agree on a definition and diagnostic criteria of radiculopathy, as well as the definition and standardisation of manual techniques, to analyse the effectiveness of manual therapy in cervical radiculopathy in depth.

Indexed as

Cervical VertebraeClinical Trials as TopicElectromyographyHumansMusculoskeletal ManipulationsNeck PainRadiculopathyRange of Motion, Articular

Identifiers

PMID34189141
PMCPMC8195637
OpenAlexW3166876141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.