Evidence map›Paper›PMID 34188993›Full record

ArticleCureus2021

Advanced Esophageal Squamous Cell Carcinoma in Young Female Patient With Durable Complete Response on Treatment.

Natalia Jankarashvili, Tamar Melkadze, Mariam Tchiabrishvili, Armaz Mariamidze, Giorgi Arveladze

Abstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Natalia JankarashviliDepartment of Radiation Oncology, Academician Fridon Todua Medical Center, Tbilisi, GEO.
Tamar MelkadzeDepartment of Clinical Oncology, Academician Fridon Todua Medical Center, Tbilisi, GEO.
Mariam TchiabrishviliDepartment of Radiation Oncology, Academician Fridon Todua Medical Center, Tbilisi, GEO.
Armaz MariamidzeDepartment of Pathology, Pathology Research Center, Tbilisi, GEO.
Giorgi ArveladzeDepartment of Radiation Oncology, David Tvildiani Medical University, Tbilisi, GEO.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal carcinoma is the seventh most common cancer and the sixth most lethal cancer worldwide. There are two main histological types of esophageal carcinoma: adenocarcinoma (AC) and squamous cell carcinoma (SCC). Both histological types are more common in males than females. Menopause is an independent risk factor for esophageal cancer while usage of hormonal therapy (estrogen plus progesterone) is associated with a lower risk of esophageal SCC in postmenopausal women. Gender differences have an impact on SCC incidence, however, it is unclear if gender has a prognostic value for survival. The present case report describes a young woman who developed SCC of the esophagus. The disease was diagnosed in the locally advanced stage. Definitive chemo-radiotherapy induced complete response. These findings might suggest that in young women esophageal SCC may have a better prognosis.

Indexed as

chemoradiotherapyesophageal squamous cell carcinomafemalegender rolelocally advanced

Identifiers

PMID34188993
PMCPMC8231733

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.