ArticleJournal of virus eradication2021
Hepatitis C in Uganda: Identification of infected blood donors for micro-elimination.
Article in Journal of virus eradication, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 10 citations in OpenAlex.
- Prevalence and socio-demographic factors associated with transfusion transmissible infections among voluntary blood donors in Kigali, Rwanda.BMC infectious diseases · 2026Article
- [Transfusion risk in sub-Saharan Africa: current situation and challenges specific to the Democratic Republic of Congo].Medecine tropicale et sante internationale · 2025Review
- Management of chronic hepatitis B in Uganda: A five-year experience following the initiation of a national sensitization and care campaign.Journal of virus eradication · 2025Article
- Prevalence trends of transfusion-transmitted infections at a tertiary private hospital blood bank in Uganda: a retrospective 6-year review (2017-2022).BMC infectious diseases · 2025Article
- Barriers and facilitators of integrated hepatitis B, C, and HIV screening among pregnant mothers and newborns attending maternal and newborn clinics in Koboko District, Uganda: a qualitative inquiry of providers' perspective.BMC infectious diseases · 2025Article
- Article
- High false discovery rate of the Architect anti-HCV screening test in blood donors in Uganda and evaluation of an algorithm for confirmatory testing.Vox sanguinis · 2022Article
- Hepatitis C virus seroprevalence among people with sickle cell disease in Uganda: a cross-sectional study.Therapeutic advances in infectious diseaseArticle
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThe drive to eliminate viral hepatitis by 2030 is underway. However, locally generated data on active infection is required to focus such efforts. We performed a regionally-inclusive survey to determine prevalence of active HCV, genotypes and related factors among Ugandan blood donors.
methodsParticipants from regional blood banks and blood collection centers were surveyed for information on demographic, clinical and lifestyle factors. Blood was assayed for HCV infection, HCV genotypes and subtypes. Logistic regression was performed to determine factors associated with active HCV infection.
resultsOf 1243 participants, 1041 (83.7%) were male, average age (SD), 27.7 (9.8). Prevalence of active HCV infection was 7.8% and we identified 3 genotypes. Median age (adj. OR (95% CI) = 1.03 (1.01-1.06), p-value = 0.040)), Northern region of birth versus Central or Eastern (adj. OR (95% CI) = 10.25 (2.65-39.68), p-value = 0.001)), Northern residence, versus Central or Eastern (adj. OR (95% CI) = 0.23 (0.08-0.65), p-value = 0.006)), and being married (versus single/divorced) adj. OR 2.49(1.3-4.79), p-value = 0.006 were associated with active HCV infection.
conclusionTargeted interventions in at-risk populations coupled with linkage to care and treatment will help achieve the WHO elimination goals in this setting.
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