Evidence map›Paper›PMID 34188905›Full record

ArticleAnnals of medicine and surgery (2012)2021

Paraplegia due to medullary compression caused by a large cell neuroendocrine carcinoma of the urinary bladder: A case report.

Ghassen Tlili, Houssem Ammar, Wiem Majdoub, Sonia Dziri, Waad Farhat, Emir Acacha, Rahul Gupta, Najmeddine Jalleli, Awatef Azzabi, Mehdi Jaidane

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Annals of medicine and surgery (2012), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Ghassen TliliDepartment of Urology, Sahloul Hospital, Sousse, Tunisia.
Houssem AmmarDepartment of Gastrointestinal Surgery, Sahloul Hospital, Sousse, Tunisia.
Wiem MajdoubDepartment of Anatomopathology, Sahloul Hospital, Sousse, Tunisia.
Sonia DziriDepartment of Nephrology, Sahloul Hospital, Sousse, Tunisia.
Waad FarhatDepartment of Gastrointestinal Surgery, Sahloul Hospital, Sousse, Tunisia.
Emir AcachaDepartment of Urology, Sahloul Hospital, Sousse, Tunisia.
Rahul GuptaDepartment of Gastrointestinal Surgery, Synergy Institute of Medical Sciences, Dehradun, India.
Najmeddine JalleliDepartment of Urology, Sahloul Hospital, Sousse, Tunisia.
Awatef AzzabiDepartment of Nephrology, Sahloul Hospital, Sousse, Tunisia.
Mehdi JaidaneDepartment of Urology, Sahloul Hospital, Sousse, Tunisia.
Hôpital Sahloul · TNInstitute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeuroendocrine carcinomas of the urinary bladder are rare tumors, estimated at less than 1% of urinary bladder malignancies. They are mainly represented by small cell neuroendocrine carcinoma, while large cell neuroendocrine carcinoma (LCNEC) is rarely reported. CASE PRESENTATION: We report a case of a 49-year-old man presenting paraplegia caused by a metastatic urinary bladder LCNEC, which was managed with palliative external beam radiotherapy (EBRT) associated with MVAC chemotherapy, including methotrexate, vinblastine sulfate, doxorubicin hydrochloride (Adriamycin), and cisplatin. At the last follow-up of one year after his admission, there was a symptomatic improvement in the pain intensity.

conclusionLCNEC of the bladder was first described in 1986, and, until now, less than 40 cases have been published in the literature. To the best of our knowledge, this is the first case of primary LCNEC of the urinary bladder presenting with paraplegia.

Indexed as

Large cell neuroendocrine carcinomaParaplegia

Identifiers

PMID34188905
PMCPMC8220165
OpenAlexW3172680259

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.