ArticleJournal of oral microbiology2021
The bacterial microbiome and metabolome in caries progression and arrest.
Abstract read
In one paragraph
Article in Journal of oral microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Oral Microbiome and Metabolome Changes During Orthodontic Treatments: A Systematic Review of Limited Clinical Evidence.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Behaviour change intervention (education and text) to prevent dental caries in secondary school pupils: BRIGHT RCT, process and economic evaluation.Health technology assessment (Winchester, England) · 2024Trial
- Changes in oral microflora following 0.3% cetylpyridinium chloride-containing mouth spray intervention in adult volunteers after professional oral care: Randomized clinical study.Clinical and experimental dental research · 2023Trial
- Effects of demineralization around orthodontic brackets bonded with different adhesive agents on fatigue-based shear bond strength: an in vitro comparative study.BMC oral health · 2026Article
- Multi-omics analysis of associations between host demographics and saliva metabolome, sugar profiles, and microbiome profiles.Scientific reports · 2026Article
- Prevotella denticola promotes caries by inducing oral microbial dysbiosis.BMC oral health · 2026Article
- Supragingival Biomarker flora of Children With and Without Cariogenic Disease and Black Stains, Aged 3 to 6 Years.International dental journal · 2026Article
- The food matrix as a confounder in diet‒microbiome studies: methodological challenges and research gaps.Gut microbes reports · 2026Review
- 16S rRNA gene sequencing-based preliminary study on the differences in the microbiota between children with rampant caries and those with arrested caries.Frontiers in oral health · 2026Article
- Fastidious or rarely isolated gram-negative rods with a particular focus onClinical microbiology reviews · 2025Review
- Integrated salivary microbiome and metabolome profiling reveals ecological and functional alterations in severe early childhood caries.Journal of translational medicine · 2025Article
- Comparison of Cariogenic Organic Acid Concentrations According to Combined Use of Sucrose and Sugar Alcohols.Journal of clinical medicine · 2025Article
- Polydatin Modulates Inflammatory Cytokine Expression in Lipoteichoic Acid-Stimulated Human Dental-Pulp Stem Cells.Journal of functional biomaterials · 2025Article
- DMAHDM@MPC nanoparticles in orthodontic adhesive inhibit cariogenic bacteria and sugar metabolism to prevent enamel demineralization.Materials today. Bio · 2025Article
- Time-dependent microbiome dynamics in orthodontic thermoplastic materials: comparing PETG and TPU.Clinical oral investigations · 2025Article
- Quantitative analysis of Streptococcus mutans, Bifidobacterium, and Scardovia Wiggsiae in occlusal biofilm and their association with Visible Occlusal Plaque Index (VOPI) and International Caries Detection and Assessment System (ICDAS).European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Article
- Clinical and Technological Evaluation of the Remineralising Effect of Biomimetic Hydroxyapatite in a Population Aged 6 to 18 Years: A Randomized Clinical Trial.Bioengineering (Basel, Switzerland) · 2025Article
- Imbalance of oral microbiome homeostasis: the relationship between microbiota and the occurrence of dental caries.BMC microbiology · 2025Article
- Cariogenic Microbiota and Emerging Antibacterial Materials to Combat Dental Caries: A Literature Review.Pathogens (Basel, Switzerland) · 2025Review
- Streptococcus mutans serotyping, collagen-binding genes and Candida albicans in dentin carious lesions: a molecular approach.Clinical oral investigations · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Thamirys da Costa RosaDepartment of Pediatric Dentistry, Fluminense Federal University, Nova Friburgo, Brazil.
Aline de Almeida NevesDepartment of Pediatric Dentistry, Rio de Janeiro Federal University, Brazil.
M Andrea Azcarate-PerilMicrobiome Core Facility, University of North Carolina School of Medicine, Chapel Hill, USA.
Kimon DivarisDivision of Pediatric and Public Health, Adams School of Dentistry, University of North Carolina, Chapel Hill, USA.
Di WuDivision of Oral and Craniofacial Health Sciences, School of Dentistry, University of North Carolina, Chapel Hill, USA.
Hunyong ChoDepartment of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, USA.
Kevin MossDivision of Oral and Craniofacial Health Sciences, School of Dentistry, University of North Carolina, Chapel Hill, USA.
Bruce J PasterDepartment of Microbiology, Forsyth Institute, Cambridge, USA.
Tsute ChenDepartment of Microbiology, Forsyth Institute, Cambridge, USA.
Liana B Freitas-FernandesDepartment of Pediatric Dentistry, Rio de Janeiro Federal University, Brazil.
Tatiana K S FidalgoNational Center for Nuclear Magnetic Resonance, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Ricardo Tadeu LopesLaboratory of Nuclear Instrumentation, Federal University of Rio de Janeiro, Rio De Janeiro, Brazil.
Ana Paula ValenteNational Center for Nuclear Magnetic Resonance, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Roland R ArnoldDivision of Diagnostic Sciences, Adams School of Dentistry, University of North Carolina, Chapel Hill, USA.
Apoena de Aguiar RibeiroDivision of Diagnostic Sciences, Adams School of Dentistry, University of North Carolina, Chapel Hill, USA.ORCID https://orcid.org/0000-0001-7702-6178
Funding
Genome-Wide Association Study of Early Childhood CariesU01DE025046 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DIVARIS, KIMON · 2015 to 2019
$8.4MInvestigating the microbial basis of early childhood caries via metagenomics and metatranscriptomics analysesR03DE028983 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WU, DI · 2019 to 2020
$299kNIDCR NIH HHS R03 DE028983NIDCR NIH HHS U01 DE025046
Abstract
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Indexed as
BacteriaDental cariesmetabolomemicroctoral bacterial microbiome
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.