ReviewThe Japanese dental science review2020
Current perspectives on dental adhesion: (1) Dentin adhesion - not there yet.
Review in The Japanese dental science review, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
127 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Influence of Operative Techniques on Clinical and Laboratory Outcomes in Class II Resin-Based Composite Restorations: A Systematic Review.Medical science monitor : international medical journal of experimental and clinical research · 2026Pooled it
- Effect of mussel-inspired primers on resin-dentin bonding interface stability: A systematic review and meta-analysis.European journal of oral sciences · 2025Pooled it
- Clinical Performance of Glass Ionomer Cement in Load-Bearing Restorations: A Systematic Review.Medical science monitor : international medical journal of experimental and clinical research · 2024Pooled it
- Pooled it
- Effects of Er: YAG, Er,Cr: YSGG, and Nd: YAG laser irradiation and adhesive systems on the immediate and long-term bond strength of dentin: a systematic review and meta-analysis.Lasers in medical science · 2023Pooled it
- A two-year randomized clinical trial of bulk-fill and ion-releasing composites with universal adhesives in class V carious lesions.Clinical oral investigations · 2026Trial
- Prospective, randomized, paired-comparison clinical trial of a new universal adhesive in posterior composite restorations: A 2-year evaluation.Clinical oral investigations · 2026Trial
- Clinical evaluation of different solvent type and HEMA-content of universal adhesive systems in non-carious cervical lesions: a two-year double-blind split-mouth randomized clinical trial.BMC oral health · 2025Trial
- Trial
- Prospective, randomized clinical trial evaluating the clinical performance of a new universal adhesive in Class I and Class II restorations at 1 year.Clinical oral investigations · 2024Trial
- Bonding strategy of a universal adhesive system containing chitosan: influence on dentin permeability, and effect on adhesive layer micromorphology.Acta odontologica latinoamericana : AOL · 2022Trial
- Two-year randomized clinical trial of different restorative techniques in non-carious cervical lesions and MMP activity in gingival crevicular fluid.Clinical oral investigations · 2022Trial
- Which is the best adhesive system for primary tooth enamel? A systematic review and network meta-analysis of bond strength data.The Japanese dental science review · 2026Review
- Adhesive-based protective strategies for enamel cracks during in-office bleaching and their effect on hydrogen peroxide penetration.Clinical oral investigations · 2026Article
- Article
- Thermo-mechanical loading of innovative "Mini-skirt" preparation design versus conventional full-coverage maxillary central incisor preparation design: an in vitro study.BMC oral health · 2026Article
- Comparison of Four Universal Adhesive Protocols for the Internal Adaptation of Composite Restorations in Primary Teeth: An In Vitro Micro-CT Study.Materials (Basel, Switzerland) · 2026Article
- Effect of Etching Protocols on the Bonding Performance of a HEMA-Free Two-Step Universal Adhesive to Caries-Affected Dentin.The journal of adhesive dentistry · 2026Article
- The Use of Bovine Teeth as an Experimental Substrate in the Evaluation of Shear in Contemporary Adhesive Systems.Polymers · 2026Article
- Functional Adhesives for a Restorative Future.Journal of functional biomaterials · 2026Review
67 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The essential goal of any adhesive restoration is to achieve a tight and long-lasting adaptation of the restorative material to enamel and dentin. The key challenge for new dental adhesives is to be simultaneously effective on two dental substrates of conflicting nature. Some barriers must be overcome to accomplish this objective. While bonding to enamel by micromechanical interlocking of resin tags within the array of microporosities in acid-etched enamel can be reliably achieved and can effectively seal the restoration margins against leakage, bonding effectively and durably to organic and humid dentin is the most puzzling task in adhesive dentistry. Much of the research and development of dental adhesives has focused on making the clinical procedure more user-friendly by reducing the number of bottles and/or steps. Although clinicians certainly prefer less complicated and more versatile adhesive materials, there is a trade-off between simplification of dental adhesives and clinical outcomes. Likewise, new materials are launched with claims of being novel and having special properties without much supporting evidence. This review article discusses dental adhesion acknowledging pioneer work in the field, highlights the substrate as a major challenge to obtain durable adhesive restorations, as well as analyzes the three adhesion strategies and their shortcomings. It also reviews the potential of chemical/ionic dental adhesion, discusses the issue of extensively published laboratory research that does not translate to clinical relevance, and leaves a few thoughts in regard to recent research that may have implications for future adhesive materials.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.