Evidence map›Paper›PMID 34188616›Full record

ArticleJournal of applied crystallography2021

Aerosol-based ligand soaking of reservoir-free protein crystals.

Breyan Ross, Stephan Krapp, Ruth Geiss-Friedlander, Walter Littmann, Robert Huber, Reiner Kiefersauer

Abstract read
In one paragraph

Article in Journal of applied crystallography, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Automated gradient equilibration of macromolecular crystals to new solution conditions.Acta crystallographica. Section F, Structural biology communications · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Breyan RossMax Planck Institut für Biochemie, D-82152 Martinsried, Germany.ORCID https://orcid.org/0000-0002-9999-2649
Stephan KrappProteros Biostructures GmbH, D-82152 Martinsried, Germany.
Ruth Geiss-FriedlanderCenter of Biochemistry and Molecular Cell Research, Albert-Ludwigs-Universität, D-79104 Freiburg, Germany.ORCID https://orcid.org/0000-0002-1720-3440
Walter LittmannATHENA Technologie Beratung GmbH, Technologiepark 13, D-33100 Paderborn, Germany.
Robert HuberMax Planck Institut für Biochemie, D-82152 Martinsried, Germany.ORCID https://orcid.org/0000-0002-0133-5334
Reiner KiefersauerMax Planck Institut für Biochemie, D-82152 Martinsried, Germany.ORCID https://orcid.org/0000-0002-4889-9559

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Soaking of macromolecular crystals allows the formation of complexes via diffusion of molecules into a preformed crystal for structural analysis. Soaking offers various advantages over co-crystallization,

Indexed as

aerosolsDPP8soakingultrasonic

Identifiers

PMID34188616
PMCPMC8202026

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.