Evidence map›Paper›PMID 34188608›Full record

ArticleMediators of inflammation2021

Sodium Houttuyfonate Ameliorates

Yuequan Zhao, YunPeng Tian, Tao Feng

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Identification of Molecular Correlations of GSDMD with Pyroptosis inAlzheimer's Disease.Combinatorial chemistry & high throughput screening · 2024
    Article
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yuequan ZhaoThe Second Ward of Neurology Department, Dongying People's Hospital, Dongying, Shandong 257091, China.
YunPeng TianThe Second Ward of Neurology Department, Dongying People's Hospital, Dongying, Shandong 257091, China.
Tao FengDepartment of Pharmacy, Dongying People's Hospital, Dongying, Shandong 257091, China.ORCID https://orcid.org/0000-0001-7223-7654
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOur research is designed to explore the function of sodium houttuyfonate (SH) on Alzheimer's disease (AD) and its potential molecular mechanisms.

methodsIn our study, the Morris water maze (MWM) test was used to assess the role of SH on spatial learning and memory deficiency in amyloid-

resultsOur data demonstrated that SH ameliorated spatial learning and memory deficiency in A

conclusionThe present study demonstrated that SH could ameliorate A

Indexed as

Amyloid beta-PeptidesPeptide FragmentsAlkanesAlzheimer DiseaseAnimalsApoptosisBrainCell SurvivalDisease Models, AnimalEnzyme-Linked Immunosorbent AssayGasderminsIntracellular Signaling Peptides and ProteinsIn Vitro TechniquesMaleMaze LearningMemory DisordersAlkanesAmyloid beta-Peptidesamyloid beta-protein (1-42)GasderminsGsdmd protein, mouseIntracellular Signaling Peptides and ProteinsNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mousePeptide FragmentsPhosphate-Binding ProteinsRNA, Messengersodium houttuyfonateSulfites

Identifiers

PMID34188608
PMCPMC8195664
OpenAlexW3172774990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.