Evidence map›Paper›PMID 34188588›Full record

ArticleNoro psikiyatri arsivi2021

Neurocognitive Functions in Bipolar Disorder in Relation to Comorbid ADHD.

Hidayet Ece Arat Çelik, Deniz Ceylan, Ceren Hidiroğlu Ongun, Ayşe Erdoğan, Devran Tan, Peren Gümüşkesen, Başak Bağci, Ayşegül Özerdem

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In one paragraph

Article in Noro psikiyatri arsivi, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hidayet Ece Arat ÇelikMaltepe University, Faculty of Medicine, Department of Psychiatry, İstanbul, Turkey.
Deniz CeylanKoç University, Faculty of Medicine, Department of Psychiatry, İstanbul, Turkey.
Ceren Hidiroğlu OngunDokuz Eylül University, Faculty of Arts, Department of Psychology, İzmir, Turkey.
Ayşe ErdoğanDokuz Eylül University, Institute of Health Sciences, Department of Neuroscience, İzmir, Turkey.
Devran TanNişantaşı University, Faculty of Economics, Administrative and Scocial Sciences, Department of Psychology, İstanbul, Turkey.
Peren GümüşkesenDokuz Eylül University, Institute of Health Sciences, Department of Neuroscience, İzmir, Turkey.
Başak BağciKatip Çelebi University, Ataturk Training and Research Hospital, Department of Psychiatry, İzmir, Turkey.
Ayşegül ÖzerdemMayo Clinic, Department of Psychiatry and Psychology, Rochester, MN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBipolar disorder (BD) and attention deficit hyperactivity disorder (ADHD) often co-occur in adult population. Both conditions present various neurocognitive and behavioral problems. We aimed to examine neurocognitive functions in adult patients with comorbid BD and ADHD (BD+ADHD) in comparison to patients with only BD, only ADHD and healthy controls (HCs).

methodAn extensive cognitive battery which evaluates verbal learning and memory, visual memory, processing speed, attention, executive functions, working memory and verbal fluency, was used to assess neurocognitive functions respectively in adult (age 18-65 years) patients with BD (n=37), ADHD (n=43), BD+ADHD (n=20) in comparison to HCs (n=51). The Multivariate Analysis of Covariance models, where age, level of education and total BIS-11 scores were included as covariates, were used for comparing neurocognitive scores among groups.

resultsBoth BD and BD+ADHD groups showed significantly poorer performance than HCs in processing speed, attention, executive functions, and verbal fluency domains. The BD group had additional significant deficits in executive functions, verbal learning and memory domains. There were no significant differences between BD and BD+ADHD groups with regards to verbal learning and memory, visual memory, processing speed, attention, executive functions, working memory and verbal fluency domains. Patients with only ADHD showed significantly poorer performance than HCs in verbal fluency domain.

conclusionsOur results show similarities in the neurocognitive functions of adults with BD and BD+ADHD across a wide range of cognitive domains. The findings point to the need for further exploration of diverging and converging neurodevelopmental trajectories of BD and ADHD.

Indexed as

attention deficit hyperactivity disorderBipolar disorderneurocognitive functions

Identifiers

PMID34188588
PMCPMC8214746

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.