Evidence map›Paper›PMID 34188522›Full record

ArticleInternational journal of general medicine2021

Polycyclic Aromatic Hydrocarbons and the Risk of Kidney Stones in US Adults: An Exposure-Response Analysis of NHANES 2007-2012.

Si Sun, Weipu Mao, Shuchun Tao, Xiangyu Zou, Shengwei Tian, Siwei Qian, Chi Yao, Guangyuan Zhang, Ming Chen

Open access · goldAbstract read
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Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Si Sun *Department of Urology, Zhongda Hospital, Southeast University, Nanjing, 210009, People's Republic of China.
Weipu Mao *Department of Urology, Zhongda Hospital, Southeast University, Nanjing, 210009, People's Republic of China.
Shuchun Tao *Department of Urology, Zhongda Hospital, Southeast University, Nanjing, 210009, People's Republic of China.
Xiangyu ZouDepartment of Urology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, People's Republic of China.
Shengwei TianDepartment of Urology, Zhongda Hospital, Southeast University, Nanjing, 210009, People's Republic of China.
Siwei QianDepartment of Urology, Zhongda Hospital, Southeast University, Nanjing, 210009, People's Republic of China.
Chi YaoDepartment of Urology, Zhongda Hospital, Southeast University, Nanjing, 210009, People's Republic of China.
Guangyuan ZhangDepartment of Urology, Zhongda Hospital, Southeast University, Nanjing, 210009, People's Republic of China.
Ming ChenDepartment of Urology, Zhongda Hospital, Southeast University, Nanjing, 210009, People's Republic of China.
Zhongda Hospital Southeast University · CNShanghai Children's Medical Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolycyclic aromatic hydrocarbons (PAHs) exposure may cause various diseases. However, the association between PAHs exposure and kidney stones remains unclear. The purpose of this study was to examine the relationship between PAHs and the risk of kidney stones in the US population.

methodsThe study included a total of 30,442 individuals (≥20 years) from the 2007-2012 National Health and Nutrition Examination Survey (NHANES). Nine urinary PAHs were included in this study. Logistic regression and dose-response curves were used to evaluate the association between PAHs and the risk of kidney stones.

resultsWe selected 4385 participants. The dose-response curves showed a significant positive association between total PAHs, 2-hydroxynaphthalene, 1-hydroxyphenanthrene, 2-hydroxyphenanthrene, 9-hydroxyfluorene and the risk of kidney stones after adjusting for confounding factors. Compared with the low group, an increased risk of kidney stones was observed in the high group of total PAHs [OR (95% CI), 1.32 (1.06-1.64), P=0.013], 2-hydroxynaphthalene [OR (95% CI), 1.37 (1.10-1.71), P=0.005], 1-hydroxyphenanthrene [OR (95% CI), 1.24 (1.00-1.54), P=0.046] and 9-hydroxyfluorene [OR (95% CI), 1.36 (1.09-1.70), P=0.007].

conclusionHigh levels of PAHs were positively associated with the risk of kidney stones in the US population.

Indexed as

cross-sectional surveykidney stonesNHANESpolycyclic aromatic hydrocarbons

Identifiers

PMID34188522
PMCPMC8232959
OpenAlexW3174781984

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.