Evidence map›Paper›PMID 34188503›Full record

ArticleClinicoEconomics and outcomes research : CEOR2021

Centers of Excellence Implementation for Treating Rheumatoid Arthritis in Colombia: A Cost-Analysis.

Pedro Santos-Moreno, Nelson J Alvis-Zakzuk, Laura Villarreal-Peralta, Maria Carrasquilla-Sotomayor, Fernando de la Hoz-Restrepo, Nelson Alvis-Guzmán

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Article in ClinicoEconomics and outcomes research : CEOR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pedro Santos-MorenoRheumatology, Biomab IPS, Bogotá, Colombia.ORCID 0000-0001-7802-0317
Nelson J Alvis-ZakzukDepartment of Health Sciences, Universidad de la Costa -CUC, Barranquilla, Colombia.ORCID 0000-0001-9382-214X
Laura Villarreal-PeraltaRheumatology, Biomab IPS, Bogotá, Colombia.
Maria Carrasquilla-SotomayorDepartment of Health Technology Assessment, ALZAK Foundation, Cartagena, Colombia.
Fernando de la Hoz-RestrepoDepartment of Public Health, Universidad Nacional de Colombia, Bogotá, DC, Colombia.
Nelson Alvis-GuzmánDepartment of Health Sciences, Universidad de la Costa - CUC, Barranquilla, Colombia.ORCID 0000-0001-9458-864X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealth systems need to optimize the use of resources, especially in high-cost diseases as rheumatoid arthritis (RA). We aimed to evaluate the efficiency of using centers of excellence (CoE) as a strategy for improving RA treatment in Colombia.

methodsA cost description analysis was carried out using the standard costing technique. We estimated the costs of medical consultations, laboratories, images, and medications for RA. Categories of care standards stratified by severity were defined using the disease activity score in 28 joints (DAS28). We evaluated the impact, in terms of costs (US dollars), for providing RA clinical care for a previously described cohort using the CoE approach. Statistical analyses were performed in Microsoft Excel

resultsExpenditure on therapeutic drugs increases as the severity of RA increases. Drugs represent 53.6% of the total cost for the low disease activity (LDA) stage, 75.2% for moderate disease activity (MDA), 88.5% for severe disease activity (SDA) and 97% for SDA with biologic treatment (SDA+Biologic). Treating 968 patients would cost US$612,639 (US$487,978-1,220,160) at baseline, per year. After a year of follow-up at the CoE, treating the same patients would cost US$388,765 (US$321,710-708,476), which implies potential cost-savings of up to US$223,874 per year.

conclusionThe strategy of providing clinical care for RA through CoE can save US$231.3 per patient-per year. The results of our study show that CoE could greatly impact the public policies dealing with treatment of RA in Colombia. Applying the CoE model in our country would both improve health outcomes, as well as being more efficient in terms of costs.

Indexed as

cost-analysiscost-savingsrheumatoid arthritistreat to target

Identifiers

PMID34188503
PMCPMC8236254

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.