Evidence map›Paper›PMID 34188261›Full record

ArticleIndian journal of anaesthesia2021

Effects of intraoperative inverse ratio ventilation on postoperative pulmonary function tests in the patients undergoing laparoscopic cholecystectomy: A prospective single blind study.

Vijay Adabala, Mukesh Tripathi, Priyanka Gupta, Prabakaran Parameswaran, Revanth Challa, Ajit Kumar

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In one paragraph

Article in Indian journal of anaesthesia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Vijay AdabalaDepartment of Anaesthesia, 6 level, Medical College Building, All India Institute of Medical Sciences (A.I.I.M.S.), Rishikesh, Uttarakhand, India.
Mukesh TripathiDepartment of Anaesthesia, 6 level, Medical College Building, All India Institute of Medical Sciences (A.I.I.M.S.), Rishikesh, Uttarakhand, India.
Priyanka GuptaDepartment of Anaesthesia, 6 level, Medical College Building, All India Institute of Medical Sciences (A.I.I.M.S.), Rishikesh, Uttarakhand, India.
Prabakaran ParameswaranDepartment of Anaesthesia, 6 level, Medical College Building, All India Institute of Medical Sciences (A.I.I.M.S.), Rishikesh, Uttarakhand, India.
Revanth ChallaDepartment of Anaesthesia, 6 level, Medical College Building, All India Institute of Medical Sciences (A.I.I.M.S.), Rishikesh, Uttarakhand, India.
Ajit KumarDepartment of Anaesthesia, 6 level, Medical College Building, All India Institute of Medical Sciences (A.I.I.M.S.), Rishikesh, Uttarakhand, India.
All India Institute of Medical Sciences Rishikesh · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsInduction of general anaesthesia is associated with development of atelectasis in the lungs, which may further lead to postoperative pulmonary complications. Inverse ratio ventilation (IRV) has shown to improve oxygenation and minimise further lung injury in patients with acute respiratory distress syndrome. We evaluated the safety and effectiveness of IRV on intraoperative respiratory mechanics and postoperative pulmonary function tests (PFTs).

methodsIn a prospective, controlled study, 128 consecutive patients with normal preoperative PFTs who underwent elective laparoscopic cholecystectomy were randomised into IRV and conventional ventilation groups. Initially, all patients were ventilated with settings of tidal volume 8 mL/kg, respiratory rate 12/min, inspiratory/expiratory ratio (I: E) = 1:2, positive end expiratory pressure = 0. Once the pneumoperitoneum was created, the conventional group patients were continued to be ventilated with same settings. However, in the IRV group, I: E ratio was changed to 2:1. Peak pressure (Ppeak), Plateau pressure (Pplat) and lung compliance were measured. Haemodynamic parameters and arterial blood gas values were also measured. PFTs were repeated in postoperative period. Statistical tool included Chi-square test.

resultsThere was no significant difference in PFTs in patients who underwent IRV as compared to conventional ventilation [forced vital capacity (FVC) 2.52 ± 0.13 versus 2.63 ± 0.16,

conclusionIntraoperative IRV led to reduced airway pressures; however, it did not prevent deterioration of PFTs in postoperative period.

Indexed as

Atelectasisgeneral anaesthesiainverse ratio ventilationlaparoscopic cholecystectomylung protective ventilationpostoperative pulmonary complications

Identifiers

PMID34188261
PMCPMC8191195
OpenAlexW3162942364

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.