Trial reportScientific reports2021
Uncovering complexity details in actigraphy patterns to differentiate the depressed from the non-depressed.
Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Role of Digital Biomarkers in Physiological Signal-Based Depression Assessment: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2026Pooled it
- Actigraphically measured psychomotor slowing in depression: systematic review and meta-analysis.Psychological medicine · 2022Pooled it
- Effects of dynamic bedroom lighting on measures of sleep and circadian rest-activity rhythm in inpatients with major depressive disorder.Scientific reports · 2022Trial
- Dose-response relationship between accelerometer-measured physical activity and depression: evidence from the UK Biobank.Translational psychiatry · 2025Article
- Chaos to clarity: interpreting time series complexity metrics with an application to depression.Discover mental health · 2025Review
- Wearables in Chronomedicine and Interpretation of Circadian Health.Diagnostics (Basel, Switzerland) · 2025Review
- Aging and activity patterns: actigraphy evidence from NHANES studies.Frontiers in systems biology · 2025Article
- Article
- Mother-child autonomic nervous system interaction as an indication of parental stress: 24-hour cross recurrence plot analysis.PloS one · 2025Article
- Motor actions across psychiatric disorders: A research domain criteria (RDoC) perspective.Clinical psychology review · 2024Review
- General spectral characteristics of human activity and its inherent scale-free fluctuations.Scientific reports · 2024Article
- An exploration of actigraphy in the context of ketamine and treatment-resistant depression.International journal of methods in psychiatric research · 2023Article
- The Mediating Role of Perceived Stress and Academic Procrastination between Physical Activity and Depressive Symptoms among Chinese College Students during the COVID-19 Pandemic.International journal of environmental research and public health · 2022Article
- Multiscale entropy analysis of retinal signals reveals reduced complexity in a mouse model of Alzheimer's disease.Scientific reports · 2022Article
- Building and Realizing the Obstetrics and Gynecology Nursing Management Platform by Computer Information Technology under the Concept of Mindfulness Intervention.Journal of healthcare engineering · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While the negative association between physical activity and depression has been well established, it is unclear what precise characteristics of physical activity patterns explain this association. Complexity measures may identify previously unexplored aspects of objectively measured activity patterns, such as the extent to which individuals show repetitive periods of physical activity and the diversity in durations of such repetitive activity patterns. We compared the complexity levels of actigraphy data gathered over 4 weeks ([Formula: see text] data points each) for every individual, from non-depressed ([Formula: see text]) and depressed ([Formula: see text]) groups using recurrence plots. Significantly lower levels of complexity were detected in the actigraphy data from the depressed group as compared to non-depressed controls, both in terms of lower mean durations of periods of recurrent physical activity and less diversity in the duration of these periods. Further, diagnosis of depression was not significantly associated with mean activity levels or measures of circadian rhythm stability, and predicted depression status better than these.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.