ArticleScientific reports2021
Noncytotoxic silver nanoparticles as a new antimicrobial strategy.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 89 citations in OpenAlex.
- Are Silver and Gold Nanoparticles Obtained by 'Green' Synthesis Biocompatible?Nanomaterials (Basel, Switzerland) · 2026Review
- Contact-Accessible Silver Nanoparticle-Decorated Electrospun Carbon Fibers for Microplastics Detection by SERS.Materials (Basel, Switzerland) · 2026Article
- Microbial secretome-mediated nanotechnology: an antibacterial strategy for future.Archives of microbiology · 2026Review
- Sustainable nanomaterials for precision dental medicine: green synthesis, therapeutic applications, and future directions.Journal of nanobiotechnology · 2026Review
- Harnessing nature for dual action: silver nanoparticles synthesized from guava leaf extract for photocatalytic degradation of methyl red and antibacterial applications.RSC advances · 2025Article
- A Minor Groove Binder with Significant Cytotoxicity on Human Lung Cancer Cells: The Potential of Hesperetin Functionalised Silver Nanoparticles.Journal of fluorescence · 2024Article
- Mapping a sustainable approach: biosynthesis of lactobacilli-silver nanocomposites using whey-based medium for antimicrobial and bioactivity applications.Microbial cell factories · 2024Article
- Infection-Free and Enhanced Wound Healing Potential of Alginate Gels Incorporating Silver and Tannylated Calcium Peroxide Nanoparticles.International journal of molecular sciences · 2024Article
- High-Throughput Screening Method UsingMicroorganisms · 2024Article
- Rosmarinic Acid-RichMolecules (Basel, Switzerland) · 2024Article
- Antibacterial efficacy of novel bismuth-silver nanoparticles synthesis onFrontiers in microbiology · 2024Article
- Nanobiomaterials: exploring mechanistic roles in combating microbial infections and cancer.Discover nano · 2023Review
- Microalga Broths Synthesize Antibacterial and Non-Cytotoxic Silver Nanoparticles Showing Synergy with Antibiotics and Bacterial ROS Induction and Can Be Reused for Successive AgNP Batches.International journal of molecular sciences · 2023Article
- Biomaterial composed of chitosan, riboflavin, and hydroxyapatite for bone tissue regeneration.Scientific reports · 2023Article
- Characterization and investigation of biological properties of silver nanoparticle-doped hydroxyapatite-based surfaces on zirconium.Scientific reports · 2023Article
- Characterization and investigation of electrochemical and biological properties of antibacterial silver nanoparticle-deposited TiOScientific reports · 2023Article
- Fungal-Mediated Silver Nanoparticle and Biochar Synergy against Colorectal Cancer Cells and Pathogenic Bacteria.Antibiotics (Basel, Switzerland) · 2023Article
- One-Step Phytofabrication Method of Silver and Gold Nanoparticles UsingPharmaceutics · 2023Article
- TA-AgNPs/Alginate Hydrogel and Its Potential Application as a Promising Antibiofilm Material against Polymicrobial Wound Biofilms Using a Unique Biofilm Flow Model.Microorganisms · 2022Article
- Green Extracellular Synthesis of Silver Nanoparticles byMolecules (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drug-resistance of bacteria is an ongoing problem in hospital treatment. The main mechanism of bacterial virulency in human infections is based on their adhesion ability and biofilm formation. Many approaches have been invented to overcome this problem, i.e. treatment with antibacterial biomolecules, which have some limitations e.g. enzymatic degradation and short shelf stability. Silver nanoparticles (AgNPs) may be alternative to these strategies due to their unique and high antibacterial properties. Herein, we report on yeast Saccharomyces cerevisiae extracellular-based synthesis of AgNPs. Transmission electron microscopy (TEM) revealed the morphology and structure of the metallic nanoparticles, which showed a uniform distribution and good colloid stability, measured by hydrodynamic light scattering (DLS). The energy dispersive X-ray spectroscopy (EDS) of NPs confirms the presence of silver and showed that sulfur-rich compounds act as a capping agent being adsorbed on the surface of AgNPs. Antimicrobial tests showed that AgNPs inhibit the bacteria growth, while have no impact on fungi growth. Moreover, tested NPs was characterized by high inhibitory potential of bacteria biofilm formation but also eradication of established biofilms. The cytotoxic effect of the NPs on four mammalian normal and cancer cell lines was tested through the metabolic activity, cell viability and wound-healing assays. Last, but not least, ability to deep penetration of the silver colloid to the root canal was imaged by scanning electron microscopy (SEM) to show its potential as the material for root-end filling.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.