ArticleScientific reports2021
An increasing role of pyrethroid-resistant Anopheles funestus in malaria transmission in the Lake Zone, Tanzania.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Baseline malaria burden and pyrethroid resistance in Muheza, Tanzania informing a cluster randomized trial of the 3D window screens.Scientific reports · 2026Trial
- A noninferiority cluster randomised evaluation of a broflanilide indoor residual spraying insecticide, VECTRON T500, for malaria vector control in Tanzania.Scientific reports · 2025Trial
- Trial
- Differential impact of dual-active ingredient long-lasting insecticidal nets on primary malaria vectors: a secondary analysis of a 3-year, single-blind, cluster-randomised controlled trial in rural Tanzania.The Lancet. Planetary health · 2023Trial
- Trial
- Modelling the impact of adopting new-generation insecticide-treated nets on malaria transmission and insecticide resistance.Parasites & vectors · 2026Article
- Signature of resistance gene evolution and pyrethroid resistance escalation in the major malaria vector Anopheles funestus across Kenyan malaria-endemic regions separated by the Rift Valley.Infectious diseases of poverty · 2026Article
- Updating Anopheles funestus group members in Burkina Faso: species distribution and contribution to malaria transmission.Malaria journal · 2026Article
- Insecticide resistance profiles of Anopheles arabiensis and relationship with Microsporidia MB infection in two rice agroecosystems in Kenya.Parasites & vectors · 2026Article
- Modified cone bioassay methods for evaluating chlorfenapyr indoor residual spray.MalariaWorld journal · 2026Article
- Spatial Distribution and Biodiversity ofTropical medicine and infectious disease · 2025Article
- A large-scale mosquito larviciding in Tanga Region, Tanzania, reduced mosquito densities to varying degrees across malaria transmission risk strata.Scientific reports · 2025Article
- Modelling the impact of different intervention packages for malaria control under varying intensities of pyrethroid resistance.Malaria journal · 2025Article
- Contrasting vector competence of three main East African Anopheles malaria vector mosquitoes for Plasmodium falciparum.Scientific reports · 2025Article
- Two highly selected mutations in the tandemly duplicated CYP6P4a and CYP6P4b genes drive pyrethroid resistance in Anopheles funestus in West Africa.BMC biology · 2024Article
- Societal uses of the main water bodies inhabited by malaria vectors and implications for larval source management.Malaria journal · 2024Article
- Entomological survey of sibling species in the Anopheles funestus group in Tanzania confirms the role of Anopheles parensis as a secondary malaria vector.Parasites & vectors · 2024Article
- Tiny Green Army: Fighting Malaria with Plants and Nanotechnology.Pharmaceutics · 2024Review
- Genetic markers associated with the widespread insecticide resistance in malaria vector Anopheles funestus populations across Tanzania.Parasites & vectors · 2024Article
- Characterization of the Tissue and Strain-Specific Microbiota ofTropical medicine and infectious disease · 2024Article
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15 authors.
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Abstract
Anopheles funestus is playing an increasing role in malaria transmission in parts of sub-Saharan Africa, where An. gambiae s.s. has been effectively controlled by long-lasting insecticidal nets. We investigated vector population bionomics, insecticide resistance and malaria transmission dynamics in 86 study clusters in North-West Tanzania. An. funestus s.l. represented 94.5% (4740/5016) of all vectors and was responsible for the majority of malaria transmission (96.5%), with a sporozoite rate of 3.4% and average monthly entomological inoculation rate (EIR) of 4.57 per house. Micro-geographical heterogeneity in species composition, abundance and transmission was observed across the study district in relation to key ecological differences between northern and southern clusters, with significantly higher densities, proportions and EIR of An. funestus s.l. collected from the South. An. gambiae s.l. (5.5%) density, principally An. arabiensis (81.1%) and An. gambiae s.s. (18.9%), was much lower and closely correlated with seasonal rainfall. Both An. funestus s.l. and An. gambiae s.l. were similarly resistant to alpha-cypermethrin and permethrin. Overexpression of CYP9K1, CYP6P3, CYP6P4 and CYP6M2 and high L1014S-kdr mutation frequency were detected in An. gambiae s.s. populations. Study findings highlight the urgent need for novel vector control tools to tackle persistent malaria transmission in the Lake Region of Tanzania.
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