ArticleScientific reports2021
Concept for using magnetic particle imaging for intraoperative margin analysis in breast-conserving surgery.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic accuracy and surgical outcomes of fluorescence-guided surgery in breast cancer: a systematic review and meta-analysis.World journal of surgical oncology · 2026Pooled it
- Imaging of Artificial Tumor Models in an Anatomical Breast Phantom with a Single-Sided Magnetic Particle Imaging Scanner.Tomography (Ann Arbor, Mich.) · 2026Article
- Monitoring biological effects of somatic cell genome editing.Nature reviews. Genetics · 2026Review
- Magnetoelectric Nanoparticle-Based Wireless Brain-Computer Interface: Underlying Physics and Projected Technology Pathway.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Magnetic nanoparticles for cancer theranostics.Biomedical physics & engineering express · 2026Review
- Antibody-Protein L Functionalized Microparticles for Detection of Surface Markers in Heterogeneous Colorectal Lesions.bioRxiv : the preprint server for biology · 2025Article
- Cold Quad-Modal Nanocomplex for Precise and Quantitative In Vivo Stem Cell Tracking.Advanced functional materials · 2025Article
- Development of Iron Oxide Nanochains as a Sensitive Magnetic Particle Imaging Tracer for Cancer Detection.ACS applied materials & interfaces · 2025Article
- Foundational insights for theranostic applications of magnetoelectric nanoparticles.Nanoscale horizons · 2025Review
- Magnetic particle imaging angiography of the femoral artery in a human cadaveric perfusion model.Communications medicine · 2025Article
- Non-FFP-Based Magnetic Particle Imaging (NFMPI) with an Open-Type RF Coil System: A Feasibility Study.Sensors (Basel, Switzerland) · 2025Article
- Tomographic Magnetic Particle Imaging With a Single-Sided Field-Free Line Scanner.IEEE transactions on bio-medical engineering · 2024Article
- Assessing the efficacy of intraoperative fluorescence imaging for tumor margin identification in breast conserving surgery.Bioinformation · 2024Article
- Harmonic dependence of thermal magnetic particle imaging.Scientific reports · 2023Article
- Principles and applications of magnetic nanomaterials in magnetically guided bioimaging.Materials today physics · 2023Article
- Implementation of the surface gradiometer receive coils for the improved detection limit and sensitivity in the single-sided MPI scanner.Physics in medicine and biology · 2022Article
- Recent developments of the reconstruction in magnetic particle imaging.Visual computing for industry, biomedicine, and art · 2022Review
- Nanotechnology-Assisted Cell Tracking.Nanomaterials (Basel, Switzerland) · 2022Review
- Advanced Magnetic Resonance Imaging (MRI) Techniques: Technical Principles and Applications in Nanomedicine.Cancers · 2022Review
- Applications of Magnetic Particle Imaging in Biomedicine: Advancements and Prospects.Frontiers in physiology · 2022Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Breast-conserving surgery (BCS) is a commonly utilized treatment for early stage breast cancers but has relatively high reexcision rates due to post-surgical identification of positive margins. A fast, specific, sensitive, easy-to-use tool for assessing margins intraoperatively could reduce the need for additional surgeries, and while many techniques have been explored, the clinical need is still unmet. We assess the potential of Magnetic Particle Imaging (MPI) for intraoperative margin assessment in BCS, using a passively or actively tumor-targeted iron oxide agent and two hardware devices: a hand-held Magnetic Particle detector for identifying residual tumor in the breast, and a small-bore MPI scanner for quickly imaging the tumor distribution in the excised specimen. Here, we present both hardware systems and demonstrate proof-of-concept detection and imaging of clinically relevant phantoms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.