Evidence map›Paper›PMID 34187933›Full record

ArticleLife science alliance2021

Negative correlation of single-cell

Carla Regina, Ebrahem Hamed, Geoffroy Andrieux, Sina Angenendt, Michaela Schneider, Manching Ku, Marie Follo, Marco Wachtel, Eugene Ke, Ken Kikuchi and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life science alliance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 4 countries.

Carla ReginaDivision of Pediatric Hematology and Oncology, Department of Pediatric and Adolescent Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.
Ebrahem HamedDivision of Pediatric Hematology and Oncology, Department of Pediatric and Adolescent Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.ORCID 0000-0002-3595-677X
Geoffroy AndrieuxInstitute of Medical Bioinformatics and Systems Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Sina AngenendtDivision of Pediatric Hematology and Oncology, Department of Pediatric and Adolescent Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.ORCID 0000-0003-0827-7613
Michaela SchneiderDivision of Pediatric Hematology and Oncology, Department of Pediatric and Adolescent Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.
Manching KuDivision of Pediatric Hematology and Oncology, Department of Pediatric and Adolescent Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.ORCID 0000-0001-5168-4308
Marie FolloDepartment of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID 0000-0002-3090-7442
Marco WachtelUniversity Children's Hospital, Children's Research Center and Department of Oncology, Zürich, Switzerland.
Eugene KeDepartment of Microbiology, Immunology and Cancer Biology, School of Medicine, University of Virginia, Charlottesville, VA, USA.
Ken KikuchiDepartment of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.ORCID 0000-0003-3097-7480
Anton G HenssenExperimental and Clinical Research Center of the Max Delbrück Center and Charité Berlin, Berlin, Germany.
Beat W SchäferUniversity Children's Hospital, Children's Research Center and Department of Oncology, Zürich, Switzerland.
Melanie BoerriesInstitute of Medical Bioinformatics and Systems Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID 0000-0002-3670-0602
Amy J WagersDepartment of Stem Cell and Regenerative Biology, Harvard University, Harvard Stem Cell Institute, Cambridge, MA, USA.ORCID 0000-0002-0066-0485
Charles KellerChildren's Cancer Therapy Development Institute, Beaverton, OR, USA.ORCID 0000-0003-2505-7487
Simone HettmerDivision of Pediatric Hematology and Oncology, Department of Pediatric and Adolescent Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany simone.hettmer@uniklinik-freiburg.de.ORCID 0000-0003-1709-4448
University of Freiburg · DEUniversity Children's Hospital Zurich · CHChildren's Cancer Therapy Development Institute · USJoslin Diabetes Center · USKyoto Prefectural University of Medicine · JPMax Delbrück Center · DEUniversity of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rhabdomyosarcomas (RMS) are phenotypically and functionally heterogeneous. Both primary human RMS cultures and low-passage

Indexed as

Gene Expression Regulation, NeoplasticAnimalsApoptosisCell Line, TumorCell Transformation, NeoplasticComputational BiologyDisease Models, AnimalDisease SusceptibilityGene Expression ProfilingHumansImmunophenotypingMiceMolecular Sequence AnnotationOncogene Proteins, FusionPaired Box Transcription FactorsRhabdomyosarcomaOncogene Proteins, FusionPaired Box Transcription FactorsPAX3-FOXO1A fusion protein, human

Identifiers

PMID34187933
PMCPMC8321661
OpenAlexW3177278738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.