Evidence map›Paper›PMID 34187913›Full record

SynthesisSaudi medical journal2021

Comparison of ondansetron and tropisetron in preventing postoperative nausea and vomiting: A meta-analysis of randomized controlled trials.

Rui Wang, Xuesong Song, Yan Chen, Na Wang, Jinguo Wang

Open access · diamondAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Saudi medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rui WangFrom the Department of Computer Network (Wang R), Technology School, Jilin Business and Technology College, Changchun, Jilin; from the Department of Anesthesiology (Song, Chen, Wang N); and from the Department of Urology (Wang J), The First Hospital of Jilin University, Changchun, China.
Xuesong SongFrom the Department of Computer Network (Wang R), Technology School, Jilin Business and Technology College, Changchun, Jilin; from the Department of Anesthesiology (Song, Chen, Wang N); and from the Department of Urology (Wang J), The First Hospital of Jilin University, Changchun, China.
Yan ChenFrom the Department of Computer Network (Wang R), Technology School, Jilin Business and Technology College, Changchun, Jilin; from the Department of Anesthesiology (Song, Chen, Wang N); and from the Department of Urology (Wang J), The First Hospital of Jilin University, Changchun, China.
Na WangFrom the Department of Computer Network (Wang R), Technology School, Jilin Business and Technology College, Changchun, Jilin; from the Department of Anesthesiology (Song, Chen, Wang N); and from the Department of Urology (Wang J), The First Hospital of Jilin University, Changchun, China.
Jinguo WangFrom the Department of Computer Network (Wang R), Technology School, Jilin Business and Technology College, Changchun, Jilin; from the Department of Anesthesiology (Song, Chen, Wang N); and from the Department of Urology (Wang J), The First Hospital of Jilin University, Changchun, China.
Jilin Province Science and Technology Department · CNJilin Business and Technology College

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare the efficacy of prophylactic ondansetron and tropisetron for postoperative nausea and vomiting (PONV).

methodsA literature search was performed to identify studies that compare the efficiency of ondansetron with that of tropisetron in preventing PONV. Only randomized controlled trials updated to January, 2021 were included.

resultsThe final pooled analysis included 14 studies totaling 1705 patients and indicated that ondansetron was 39% less effective than tropisetron in preventing postoperative vomiting with a higher incidence of dizziness. However, no significant difference was detected between ondansetron and tropisetron in PONV, postoperative nausea, antiemetic treatment, and headache.

conclusionsTropisetron is superior to ondansetron in preventing postoperative vomiting.PROSPERO No: CRD42021237368.

Indexed as

AntiemeticsPostoperative Nausea and VomitingDouble-Blind MethodHumansOndansetronRandomized Controlled Trials as TopicTropisetronVomitingAntiemeticsOndansetronTropisetronantiemeticmeta-analysisondansetronpostoperativetropisetron

Identifiers

PMID34187913
PMCPMC9195535
OpenAlexW3173148117

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.