Evidence map›Paper›PMID 34187498›Full record

ArticlePediatric rheumatology online journal2021

Clinical and psychosocial stress factors are associated with decline in physical activity over time in children with juvenile idiopathic arthritis.

Liane D Heale, Kristin M Houghton, Elham Rezaei, Adam D G Baxter-Jones, Susan M Tupper, Nazeem Muhajarine, Susanne M Benseler, Gilles Boire, David A Cabral, Sarah Campillo and 26 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric rheumatology online journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Physical Activity and Sports for Children With Juvenile Idiopathic Arthritis.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2024
    Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors at 13 institutions in 1 country.

Liane D Heale *McMaster Children's Hospital and McMaster University, Hamilton, Canada.ORCID https://orcid.org/0000-0002-1726-9917
Kristin M Houghton *British Columbia Children's Hospital and University of British Columbia, 4480 Oak Street, Room K4-120, Vancouver, BC, V6H 3V4, Canada. khoughton@cw.bc.ca.ORCID http://orcid.org/0000-0001-7174-1007
Elham RezaeiJim Pattison Children's Hospital and University of Saskatchewan, Saskatoon, Canada.ORCID https://orcid.org/0000-0001-6719-8013
Adam D G Baxter-JonesUniversity of Saskatchewan, Saskatoon, Canada.ORCID https://orcid.org/0000-0003-0430-0556
Susan M TupperJim Pattison Children's Hospital and University of Saskatchewan, Saskatoon, Canada.ORCID https://orcid.org/0000-0003-3736-357X
Nazeem MuhajarineJim Pattison Children's Hospital and University of Saskatchewan, Saskatoon, Canada.ORCID https://orcid.org/0000-0001-6781-5421
Susanne M BenselerAlberta Children's Hospital and University of Calgary, Calgary, Canada.ORCID https://orcid.org/0000-0001-5756-3638
Gilles BoireCentre Intégré Universitaire de Santé et de Services Sociaux de l'Estrie- Centre Hospitalier Universitaire de Santé (CIUSSS de l'Estrie-CHUS) and University of Sherbrooke, Sherbrooke, Canada.ORCID https://orcid.org/0000-0003-2481-5821
David A CabralBritish Columbia Children's Hospital and University of British Columbia, 4480 Oak Street, Room K4-120, Vancouver, BC, V6H 3V4, Canada.ORCID https://orcid.org/0000-0003-1840-9210
Sarah CampilloMontreal Children's Hospital and McGill University, Montreal, Canada.ORCID https://orcid.org/0000-0002-2694-8671
Gaëlle ChédevilleMontreal Children's Hospital and McGill University, Montreal, Canada.ORCID https://orcid.org/0000-0001-9702-7776
Anne-Laure Chetaillele Centre Hospitalier Universitaire de Quebec, Quebec, Canada.ORCID https://orcid.org/0000-0001-6267-1270
Paul DanceyJaneway Children's Health and Rehabilitation Centre and Memorial University, St. John's, Canada.ORCID https://orcid.org/0000-0001-5998-9608
Ciaran DuffyChildren's Hospital of Eastern Ontario and University of Ottawa, Ottawa, Canada.ORCID https://orcid.org/0000-0003-2481-5450
Karen Watanabe DuffyChildren's Hospital of Eastern Ontario and University of Ottawa, Ottawa, Canada.ORCID https://orcid.org/0000-0003-0082-1485
Janet EllsworthStollery Children's Hospital and University of Alberta, Edmonton, Canada.ORCID https://orcid.org/0000-0002-8717-4737
Jaime GuzmanBritish Columbia Children's Hospital and University of British Columbia, 4480 Oak Street, Room K4-120, Vancouver, BC, V6H 3V4, Canada.ORCID https://orcid.org/0000-0001-8977-2581
Adam M HuberIWK Health Centre and Dalhousie University, Halifax, Canada.ORCID https://orcid.org/0000-0002-6616-1689
Roman JurencakChildren's Hospital of Eastern Ontario and University of Ottawa, Ottawa, Canada.ORCID https://orcid.org/0000-0003-3374-3807
Bianca LangIWK Health Centre and Dalhousie University, Halifax, Canada.ORCID https://orcid.org/0000-0002-5686-4276
Ronald M LaxerThe Hospital for Sick Children and University of Toronto, Toronto, Canada.ORCID https://orcid.org/0000-0001-6907-5148
Kimberly MorishitaBritish Columbia Children's Hospital and University of British Columbia, 4480 Oak Street, Room K4-120, Vancouver, BC, V6H 3V4, Canada.ORCID https://orcid.org/0000-0002-1389-4002
Kiem G OenThe Children's Hospital of Winnipeg and University of Manitoba, Winnipeg, Canada.ORCID https://orcid.org/0000-0002-3331-9662
Ross E PettyBritish Columbia Children's Hospital and University of British Columbia, 4480 Oak Street, Room K4-120, Vancouver, BC, V6H 3V4, Canada.ORCID https://orcid.org/0000-0001-5774-2273
Suzanne E RamseyIWK Health Centre and Dalhousie University, Halifax, Canada.ORCID https://orcid.org/0000-0003-4380-6189
Johannes RothChildren's Hospital of Eastern Ontario and University of Ottawa, Ottawa, Canada.ORCID https://orcid.org/0000-0002-6109-1503
Rayfel SchneiderThe Hospital for Sick Children and University of Toronto, Toronto, Canada.ORCID https://orcid.org/0000-0001-8636-0506
Rosie ScuccimarriMontreal Children's Hospital and McGill University, Montreal, Canada.ORCID https://orcid.org/0000-0002-7491-3318
Lynn SpiegelThe Hospital for Sick Children and University of Toronto, Toronto, Canada.ORCID https://orcid.org/0000-0003-1581-0789
Elizabeth StringerIWK Health Centre and Dalhousie University, Halifax, Canada.ORCID https://orcid.org/0000-0002-1863-2562
Shirley M L TseThe Hospital for Sick Children and University of Toronto, Toronto, Canada.ORCID https://orcid.org/0000-0002-3027-7866
Lori B TuckerBritish Columbia Children's Hospital and University of British Columbia, 4480 Oak Street, Room K4-120, Vancouver, BC, V6H 3V4, Canada.ORCID https://orcid.org/0000-0002-4314-6750
Stuart E TurveyBritish Columbia Children's Hospital and University of British Columbia, 4480 Oak Street, Room K4-120, Vancouver, BC, V6H 3V4, Canada.ORCID https://orcid.org/0000-0003-1599-1065
Rae S M YeungThe Hospital for Sick Children and University of Toronto, Toronto, Canada.ORCID https://orcid.org/0000-0003-2361-725X
Alan M RosenbergJim Pattison Children's Hospital and University of Saskatchewan, Saskatoon, Canada.ORCID https://orcid.org/0000-0002-0109-1595
BBOP Study Group
University of British Columbia · CAUniversity of Saskatchewan · CAUniversity of Toronto · CADalhousie University · CAUniversity of Ottawa · CAMontreal Children's Hospital · CACentre hospitalier universitaire de Québec · CACentre Hospitalier Universitaire de Sherbrooke · CAChildren's Hospital of Winnipeg · CAMcMaster Children's Hospital · CAMemorial University of Newfoundland · CAUniversity of Alberta · CAUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhysical activity (PA) patterns in children with juvenile idiopathic arthritis (JIA) over time are not well described. The aim of this study was to describe associations of physical activity (PA) with disease activity, function, pain, and psychosocial stress in the 2 years following diagnosis in an inception cohort of children with juvenile idiopathic arthritis (JIA).

methodsIn 82 children with newly diagnosed JIA, PA levels, prospectively determined at enrollment, 12 and 24 months using the Physical Activity Questionnaire for Children (PAQ-C) and Adolescents (PAQ-A) raw scores, were evaluated in relation to disease activity as reflected by arthritis activity (Juvenile Arthritis Disease Activity Score (JADAS-71)), function, pain, and psychosocial stresses using a linear mixed model approach. Results in the JIA cohort were compared to normative Pediatric Bone Mineral Accrual Study data derived from healthy children using z-scores.

resultsAt enrollment, PA z-score levels of study participants were lower than those in the normative population (median z-score - 0.356; p = 0.005). At enrollment, PA raw scores were negatively associated with the psychosocial domain of the Juvenile Arthritis Quality of Life Questionnaire (r = - 0.251; p = 0.023). There was a significant decline in PAQ-C/A raw scores from baseline (median and IQR: 2.6, 1.4-3.1) to 24 months (median and IQR: 2.1, 1.4-2.7; p = 0.003). The linear mixed-effect model showed that PAQ-C/A raw scores in children with JIA decreased as age, disease duration, and ESR increased. The PAQ-C/A raw scores of the participants was also negatively influenced by an increase in disease activity as measured by the JADAS-71 (p <  0.001).

conclusionCanadian children with newly diagnosed JIA have lower PA levels than healthy children. The decline in PA levels over time was associated with disease activity and higher disease-specific psychosocial stress.

Indexed as

ExerciseAdolescentArthritis, JuvenileChildCohort StudiesFemaleHumansLongitudinal StudiesMaleStress, PsychologicalTime FactorsJuvenile arthritisPhysical activityPsychosocial stress

Identifiers

PMID34187498
PMCPMC8243495
OpenAlexW3127374204

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.