ArticleThe journal of headache and pain2021
Aberrant cerebral blood flow in tinnitus patients with migraine: a perfusion functional MRI study.
Article in The journal of headache and pain, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 21 citations in OpenAlex.
- Cerebral blood flow alterations in non-auditory tinnitus: implications for cerebral venous congestion pathophysiology.Brain imaging and behavior · 2026Article
- Dehydration-associated cerebral hypoperfusion in sudden sensorineural hearing loss: an arterial spin labeling-based preliminary study.Frontiers in neurology · 2025Article
- Perfusion imaging by arterial spin labeling in migraine: A literature review.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Review
- Aberrant cerebral blood flow and functional connectivity in patients with vestibular migraine: a resting-state ASL and fMRI study.The journal of headache and pain · 2024Article
- Abnormal functional hubs in migraine patients: a resting-state MRI analysis about voxel-wise degree centrality.Journal of oral & facial pain and headache · 2024Article
- The Effects of Orofacial Myofunctional Therapy on Children with OSAHS's Craniomaxillofacial Growth: A Systematic Review.Children (Basel, Switzerland) · 2023Review
- Cerebral perfusion variance in new daily persistent headache and chronic migraine: an arterial spin-labeled MR imaging study.The journal of headache and pain · 2022Article
- Cerebral blood flow alterations in migraine patients with and without aura: An arterial spin labeling study.The journal of headache and pain · 2022Article
- Abnormalities of Thalamic Functional Connectivity in Patients with Migraine: A Resting-State fMRI Study.Pain and therapy · 2022Article
- Cerebral perfusion alterations in patients with trigeminal neuralgia as measured by pseudo-continuous arterial spin labeling.Frontiers in neuroscience · 2022Article
- Aberrant Functional Network of Small-World in Sudden Sensorineural Hearing Loss With Tinnitus.Frontiers in neuroscience · 2022Article
- Aberrant Modulations of Neurocognitive Network Dynamics in Migraine Comorbid With Tinnitus.Frontiers in aging neuroscience · 2022Article
- Cerebral Blood Flow Difference Between Acute and Chronic Tinnitus Perception: A Perfusion Functional Magnetic Resonance Imaging Study.Frontiers in neuroscience · 2021Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
purposeMigraine is often accompanied with chronic tinnitus that will affect the cerebral blood flow (CBF) and exacerbate the tinnitus distress. However, the potential relationship between migraine and tinnitus remains unclear. This study will investigate whether aberrant CBF patterns exist in migraine patients with tinnitus and examine the influence of migraine on CBF alterations in chronic tinnitus. MATERIALS AND
methodsParticipants included chronic tinnitus patients (n = 45) and non-tinnitus controls (n = 50), matched for age, sex, education, and hearing thresholds. CBF images were collected and analyzed using arterial spin labeling (ASL) perfusion functional magnetic resonance imaging (fMRI). Regions with major CBF differences between tinnitus patients and non-tinnitus controls were first detected. The effects of migraine on tinnitus for CBF alterations were further examined. Correlation analyses illustrated the association between CBF values and tinnitus severity as well as between CBF and severity of migraine.
resultsCompared with non-tinnitus controls, chronic tinnitus patients without migraine exhibited decreased CBF, primarily in right superior temporal gyrus (STG), bilateral middle frontal gyrus (MFG), and left superior frontal gyrus (SFG); decreased CBF in these regions was correlated with tinnitus distress. There was a significant effect of migraine on tinnitus for CBF in right STG and MFG. Moreover, the severity of migraine correlated negatively with CBF in tinnitus patients.
conclusionsChronic tinnitus patients exhibited reduced CBF in the auditory and prefrontal cortex. Migraine may facilitate a CBF decrease in the setting of tinnitus, which may underlie the neuropathological mechanisms of chronic tinnitus comorbid with migraine.
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