Evidence map›Paper›PMID 34187354›Full record

ArticleGenetics, selection, evolution : GSE2021

Predicting the accuracy of genomic predictions.

Jack C M Dekkers, Hailin Su, Jian Cheng

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Genetics, selection, evolution : GSE, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
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  6. Review
  7. Toward Practical Embryo Genomic Selection in Cattle: An Optimized Workflow Enabling High-Accuracy Breeding Value Prediction Without Compromising Embryo Survival.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  8. Article
  9. Integrating extensive functional annotations and multiomics of cattle enhances climate resilience prediction and mapping.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
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  13. Practical Considerations When Using Mendelian Sampling Variances for Selection Decisions in Genomic Selection Programs.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2025
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jack C M DekkersDepartment of Animal Science, Iowa State University, Ames, Iowa, USA. jdekkers@iastate.edu.ORCID https://orcid.org/0000-0003-1557-7577
Hailin SuDepartment of Animal Science, Iowa State University, Ames, Iowa, USA.
Jian ChengDepartment of Animal Science, Iowa State University, Ames, Iowa, USA.
Iowa State University · US

Funding

National Institute of Food and Agriculture 2016-10148
6 · The paper itself

Abstract

backgroundMathematical models are needed for the design of breeding programs using genomic prediction. While deterministic models for selection on pedigree-based estimates of breeding values (PEBV) are available, these have not been fully developed for genomic selection, with a key missing component being the accuracy of genomic EBV (GEBV) of selection candidates. Here, a deterministic method was developed to predict this accuracy within a closed breeding population based on the accuracy of GEBV and PEBV in the reference population and the distance of selection candidates from their closest ancestors in the reference population.

methodsThe accuracy of GEBV was modeled as a combination of the accuracy of PEBV and of EBV based on genomic relationships deviated from pedigree (DEBV). Loss of the accuracy of DEBV from the reference to the target population was modeled based on the effective number of independent chromosome segments in the reference population (M

resultsUsing simulation, both the Fisher and the selection index approach correctly predicted accuracy in the target population over time, both with and without selection. The index approach, however, resulted in estimates of M

conclusionsA deterministic method was developed to predict the accuracy of GEBV in selection candidates in a closed breeding population. The population parameter M

Indexed as

Models, GeneticSelective BreedingAnimalsGenome-Wide Association StudyLivestockPedigreePolymorphism, Single NucleotideQuantitative Trait Loci

Identifiers

PMID34187354
PMCPMC8244147
OpenAlexW3173629064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.