Evidence map›Paper›PMID 34187253›Full record

ArticlePsychology & health2022

A latent profile analysis to assess physical, cognitive and emotional symptom clusters in women with breast cancer.

Ruth G St Fleur, Sara M St George, Molly Ream, Michael H Antoni

Open access · greenAbstract read
In one paragraph

Article in Psychology & health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 15 citations in OpenAlex.

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  4. Latent profile analysis for assessing symptom clusters in women with breast cancer.Journal of cancer survivorship : research and practice · 2026
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  8. Trajectory of change in symptom patterns among patients undergoing surgery for oesophageal cancer: a prospective longitudinal study using latent transition analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ruth G St FleurDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.
Sara M St GeorgeDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0001-7263-4609
Molly ReamDepartment of Psychology, University of Miami, Coral Gables, FL, USA.
Michael H AntoniDepartment of Psychology, University of Miami, Coral Gables, FL, USA.
University of Miami · US

Funding

FACILITATING POSITIVE ADAPTATION TO BREAST CANCERR01CA064710 · NCI · UNIVERSITY OF MIAMI CORAL GABLES · PI ANTONI, MICHAEL HOWARD · 1994 to 2010
$4.2M
NCI NIH HHS R01 CA064710
6 · The paper itself

Abstract

objectiveCurrent research on the physical and psychological functioning of breast cancer survivors often takes an approach where symptoms are studied independently even though they often occur in clusters This paper aims to identify physical and psychological symptom clusters among breast cancer survivors while assessing clinical, psychosocial and demographic characteristics that predict subgroup membership.

designUsing post-surgical data collected from 240 women with stage 0-III breast cancer, symptom clusters were identified using latent profile analysis of patient-reported symptoms.

main outcome measuresBaseline measures included the Pittsburg Sleep Quality Index, the Fatigue Symptom Inventory, the Hamilton Rating Scales for depression and anxiety and the Impact of Event Scale.

resultsThree distinct classes were identified: (1) mild physical, cognitive and emotional symptoms, (2) moderate across all domains and (3) high levels of all symptoms. Lower socio-economic status, minority ethnicity, younger age, advanced disease stage along with lower self-efficacy and less internal locus of control were significantly associated with a higher likelihood of class 3 membership.

conclusionBy identifying those most at risk for severe physical and psychological symptoms in the post-surgical period, our results can guide the development of tailored interventions to optimise quality of life during breast cancer treatment.

Indexed as

Breast NeoplasmsCognitionDepressionFatigueFemaleHumansQuality of LifeSyndromeBreast cancerdisparitiessurvivorssymptom clusters

Identifiers

PMID34187253
PMCPMC10068690
OpenAlexW3174273803

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.