Evidence map›Paper›PMID 34187150›Full record

ArticleUltrasonography (Seoul, Korea)2022

Differentiation of cystic biliary atresia and choledochal cysts using prenatal ultrasonography.

Lizhu Chen, Fujiao He, Kaihui Zeng, Bing Wang, Jingyu Li, Dan Zhao, Zeyu Yang, Weidong Ren

Abstract read
In one paragraph

Article in Ultrasonography (Seoul, Korea), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  12. Biliatresone: progress in biliary atresia study.World journal of pediatrics : WJP · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lizhu ChenDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, China.
Fujiao HeDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, China.
Kaihui ZengDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, China.
Bing WangDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, China.
Jingyu LiDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, China.
Dan ZhaoDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, China.
Zeyu YangDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, China.
Weidong RenDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, China.

Funding

National Natural Science Foundation of China 81600258National Natural Science Foundation of China 81802540Shengjing Hospital
6 · The paper itself

Abstract

purposeThis study explored the performance of prenatal ultrasonography in the differential diagnosis of cystic biliary atresia (CBA) and choledochal cyst (CC).

methodsFetuses diagnosed with hepatic hilar cyst in the second trimester were included in this study. A series of prenatal ultrasound examinations were performed in the second and third trimesters. The diameter of the gallbladder (GB) and hepatic cyst were measured, as well as the wall thickness of the GB. The GB-cyst connection, visibility of the right hepatic artery (RHA), and other concomitant abnormalities were carefully evaluated. A neonatal transabdominal ultrasound examination was performed within 1 week after birth, and clinical data were followed up to 6 months after birth.

resultsBetween January 1, 2016 and January 31, 2020, 53 fetuses diagnosed with hepatic hilar cyst were recruited. Eight were excluded because they were lost to follow-up. Among the 45 cases included in this study, 10 were diagnosed with CBA and 35 with CC after birth. Statistically significant differences were found in GB width, wall thickness, change in GB width, change in cyst length, GB-cyst connection, and RHA visibility between the CBA and CC groups. GB width showed the best diagnostic performance with an area under the curve (AUC) of 0.899. The combination of GB width, GB wall thickness, and GB-cyst connection yielded a comparable AUC of 0.971.

conclusionThe GB should be carefully evaluated in fetuses with hepatic hilar cyst. Prenatal ultrasound findings could provide suggestive parameters for the differential diagnosis of CBA from CC.

Indexed as

Choledochal cystCystic biliary atresiaFetusPrenatal diagnosisUltrasonography

Identifiers

PMID34187150
PMCPMC8696141

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.