Evidence map›Paper›PMID 34186362›Full record

ArticleDiabetes & metabolic syndrome

Impact of COVID-19 on a brain damage unit.

Juan Pablo Romero, Ana Bravo-Martín, Paulina Oliva-Navarrete, Francisco Sánchez-Cuesta, Marcos Ríos-Lago, Julián Benito-León

Open access · greenAbstract read
In one paragraph

Article in Diabetes & metabolic syndrome. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Juan Pablo RomeroBrain Damage Unit, Hospital Beata María Ana, Madrid, Spain; Experimental Sciences Faculty, Francisco de Vitoria University, Madrid, Spain. Electronic address: p.romero.prof@ufv.es.
Ana Bravo-MartínBrain Damage Unit, Hospital Beata María Ana, Madrid, Spain.
Paulina Oliva-NavarreteBrain Damage Unit, Hospital Beata María Ana, Madrid, Spain.
Francisco Sánchez-CuestaExperimental Sciences Faculty, Francisco de Vitoria University, Madrid, Spain.
Marcos Ríos-LagoBrain Damage Unit, Hospital Beata María Ana, Madrid, Spain; Department of Basic Psychology, UNED, Madrid, Spain.
Julián Benito-LeónDepartment of Neurology, University Hospital "12 de Octubre", Madrid, Spain; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain; Department of Medicine, Complutense University, Madrid, Spain. Electronic address: jbenitol67@gmail.com.
Universidad Francisco de Vitoria · ESUniversidad Complutense de Madrid · ESUniversidad Nacional de Educación a Distancia · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo report on the impact of COVID-19 on a brain damage unit.

methodsWe reviewed the records of all patients admitted to our brain damage unit. The study included all the significant clinical events from the first positive qualitative real-time reverse-transcriptase-polymerase-chain-reaction assay (April 8th, 2020) for SARS-CoV-2 to the day all patients tested negative (June 8th, 2020).

resultsOf the 20 patients (14 men) (age 57.7 ± 14.9; 2-71 months after brain damage; all with a modified Rankin scale score > 4), 16 tested positive for SARS-CoV-2 and remained positive for a mean of 32.3 days (ranging from 26 to 61). One patient died from COVID-19, while 12 patients were asymptomatic and three suffered mild pneumonia without acute respiratory distress syndrome. All patients received prophylactic subcutaneous heparin. Intravenous methylprednisolone was prescribed for three patients with bilateral pneumonia with excellent results.

conclusionsMost positive cases (93.7%) were not severe. The good outcome was most likely due to the use of prophylactic anticoagulation therapy, the early use of methylprednisolone for pneumonia and the previously reported immunosuppression amid patients with brain damage. This study hopes to encourage further study into brain damage immunity.

Indexed as

Brain Damage, ChronicCOVID-19FemaleHospitalizationHumansMaleMiddle AgedRetrospective StudiesSARS-CoV-2SpainBrain damageCOVID-19SARS-CoV-2

Identifiers

PMID34186362
PMCPMC8180341
OpenAlexW3171822637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.