Evidence map›Paper›PMID 34186197›Full record

ArticleIndian pacing and electrophysiology journal

Ultrasound-guided imaging for vagus nerve stimulation to facilitate cardioneuroablation for the treatment of functional advanced atrioventricular block.

Antoni Wileczek, Anna Polewczyk, Maciej Kluk, Andrzej Kutarski, Sebastian Stec

Registry-linked trialOpen access · goldAbstract readCase Reports
In one paragraph

Article in Indian pacing and electrophysiology journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05774262 (TELE-monitoring for Standard Pacemaker Implantation or Delayed Pacemaker Implantation After Autonomic/Electrophysiologic Evaluation and Cardioneuroablation for managEment of Functional atrioventriculaR Block - Randomized Controlled Study), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05774262 narecruitingnot on this map

TELE-monitoring for Standard Pacemaker Implantation or Delayed Pacemaker Implantation After Autonomic/Electrophysiologic Evaluation and Cardioneuroablation for managEment of Functional atrioventriculaR Block - Randomized Controlled Study

TypeinterventionalSponsorAmerican Heart of PolandRan2023 to 2026Enrolled300ConditionsAtrioventricular BlockArmsPacemaker implantation, Cardioneuroablation (CNA)
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Cardioneuroablation for the treatment of reflex syncope and functional bradyarrhythmias: A Scientific Statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), the Asia Pacific Heart Rhythm Society (APHRS) and the Latin American Heart Rhythm Society (LAHRS).Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Guideline
  2. Article
  3. Article
  4. Article
  5. Fluoroscopy-free cardioneuroablation for functional bradycardia: a single-center experience.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Observational
  6. Procedural and Intermediate-term Results of the Electroanatomical-guided Cardioneuroablation for the Treatment of Supra-Hisian Second- or Advanced-degree Atrioventricular Block: the PIRECNA multicentre registry.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  7. Article
  8. Cardioneuroablation: the known and the unknown.Frontiers in cardiovascular medicine · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Antoni WileczekDivision of Electrophysiology, Cardioneuroablation, Catheter Ablation and Cardiac Stimulation, Subcarpathian Centre for Cardiovascular Intervention, 26 800-lecia st, Sanok, 38-500, Poland. Electronic address: antoniwileczek@gmail.com.
Anna PolewczykDepartment of Physiology, Pathophysiology and Clinical Immunology, Collegium Medicum, The Jan Kochanowski University in Kielce, IX Wieków Kielc 19A Alley, 25-317, Kielce, Poland; Department of Cardiac Surgery, Swietokrzyskie Cardiology Center in Kielce, Grunwaldzka 45 St., 25-736, Kielce, Poland.
Maciej KlukDepartment of Interventional Cardiology, Swietokrzyskie Cardiology Center in Kielce, Grunwaldzka 45 St., 25-736, Kielce, Poland.
Andrzej KutarskiDepartment of Cardiology Medical University of Lublin, Jaczewskiego 4 St., 20-090, Lublin, Poland.
Sebastian StecDivision of Electrophysiology, Cardioneuroablation, Catheter Ablation and Cardiac Stimulation, Subcarpathian Centre for Cardiovascular Intervention, 26 800-lecia st, Sanok, 38-500, Poland.
Jan Kochanowski University · PLMedical University of Lublin · PLSan Diego Cardiac Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case study article demonstrating successful implementation of ultrasound guided extra cardiac vagus nerve stimulation during cardioneuroablation. To our knowledge it is first published description of this technique, as most ECVS are done in the internal jugular vein bulb area. This method allows for reduction of fluoroscopy time, and most importantly reproducible vagus nerve capture especially after full bi-nodal (sinus and atrioventricular) cardioneuroablation when stimulation of vagus nerve may not give any effect in the heart. This article includes a case study with "dual component" atrioventricular block, where functional component is cured with cardioneuroablation, but structural (PR elongation) remains after procedure.

Indexed as

CardioneuroablationECANSNeuromodulationUltrasound guidedVagus nerve stimulation

Identifiers

PMID34186197
PMCPMC8577098
OpenAlexW3173172572

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.