ArticleAnnals of epidemiology2021
Association between perinatal depression and risk of attention deficit hyperactivity disorder among children: a retrospective cohort study.
Article in Annals of epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Association of parental prenatal mental health with offspring neurodevelopmental disorders: a systematic review and meta-analysis.Psychological medicine · 2026Pooled it
- Implications for the Prevention of Poverty-Related Environmental Risks for Childhood ADHD: A Narrative Review.Child psychiatry and human development · 2026Review
- Correction: Implications for the Prevention of Poverty-Related Environmental Risks for Childhood ADHD: A Narrative Review.Child psychiatry and human development · 2026Article
- Maternal migraine and offspring ADHD: triangulating the evidence.BMC medicine · 2026Article
- Single Nucleotide Polymorphisms in Orexin-1 and BDNF Receptor Genes are Associated with Increased Risk of Developing Postpartum Depression among Women with Gestational Diabetes Mellitus.Public health genomics · 2026Article
- Risk of Neurodevelopmental Disorders in Offspring of Parents with Major Depressive Disorder: A Birth Cohort Study.Journal of autism and developmental disorders · 2025Article
- Perinatal maternal mental health and offspring internalizing and externalizing difficulties from early childhood through adolescence: Rhea mother-child cohort in Crete, Greece.European child & adolescent psychiatry · 2025Article
- Postpartum Depression Increases the Risk of Childhood Attention Deficit Hyperactivity Disorder Diagnosis.Reproductive sciences (Thousand Oaks, Calif.) · 2025Article
- Investigating the Correlation Between Postpartum Management Approaches and Postpartum Depression Symptoms.Actas espanolas de psiquiatria · 2025Article
- Nucleus accumbens volume mediates the association between prenatal adversity and attention problems in youth.Development and psychopathology · 2025Article
- Trends in Postpartum Depression by Race, Ethnicity, and Prepregnancy Body Mass Index.JAMA network open · 2024Article
- Cohort profile: the U-BIRTH study on peripartum depression and child development in Sweden.BMJ open · 2023Article
- Lifetime prevalence and correlates of perinatal depression in a case-cohort study of depression.BMJ open · 2022Article
- Maternal Perinatal Depression and Risk of Neurodevelopmental Disorders in Offspring: Preliminary Results from the SOS MOOD Project.Children (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 1 country.
Funding
Abstract
purposePerinatal depression has previously been identified as a risk factor for attention deficit hyperactivity disorder (ADHD) in the offspring. Population-based studies utilizing diagnosis data are needed to better understand the relationship between these two variables. The objective of this study was to examine the association between perinatal depression and the risk of ADHD among children born during a 5 or-more-year follow-up period.
methodsThe sample was drawn from a population-based cohort of privately insured mother-child pairs within the state of Iowa. Hazard ratios for risk of ADHD by exposure to perinatal depression were estimated using adjusted Cox proportional-hazard models.
resultsAmong the 5,635 mother-child pairs, 484 mothers were diagnosed with depression during the perinatal period, and 269 children were diagnosed with ADHD. After adjustment for confounders, children born to mothers with perinatal depression were over three times more likely to be diagnosed with ADHD (HR 3.16 (95% CI 2.35, 4.23)).
conclusionsChildren born to mothers with perinatal depression were found to be at increased risk of ADHD. This finding suggests that ADHD and its adverse sequelae could be mitigated by increasing maternal depression intervention efforts as well as ADHD screening and treatment efforts targeted to this vulnerable population.
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