Evidence map›Paper›PMID 34185947›Full record

ArticleAngewandte Chemie (International ed. in English)2021

RNA-Cleaving Deoxyribozymes Differentiate Methylated Cytidine Isomers in RNA.

Anam Liaqat, Maksim V Sednev, Carina Stiller, Claudia Höbartner

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Chemical science · 2024
    Article
  3. Article
  4. Article
  5. The RNA methyltransferase METTL8 installs mNature communications · 2022
    Article
  6. Synthesis ofMonatshefte fur chemie · 2022
    Article
  7. RNA-Cleaving Deoxyribozymes Differentiate Methylated Cytidine Isomers in RNA.Angewandte Chemie (International ed. in English) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anam LiaqatInstitute of Organic Chemistry, University of Würzburg, Am Hubland, 97074, Würzburg, Germany.
Maksim V SednevInstitute of Organic Chemistry, University of Würzburg, Am Hubland, 97074, Würzburg, Germany.ORCID 0000-0001-6746-1598
Carina StillerInstitute of Organic Chemistry, University of Würzburg, Am Hubland, 97074, Würzburg, Germany.
Claudia HöbartnerInstitute of Organic Chemistry, University of Würzburg, Am Hubland, 97074, Würzburg, Germany.ORCID 0000-0002-4548-2299

Funding

European Research Council 682586
6 · The paper itself

Abstract

Deoxyribozymes are emerging as modification-specific endonucleases for the analysis of epigenetic RNA modifications. Here, we report RNA-cleaving deoxyribozymes that differentially respond to the presence of natural methylated cytidines, 3-methylcytidine (m

Indexed as

Base PairingCytidineDNA, CatalyticNucleic Acid ConformationRNARNA CleavageSubstrate Specificity3-methylcytidine5-methylcytidineCytidineDNA, CatalyticN(4)-methylcytidineRNAdeoxyribozymesepitranscriptomicsin vitro selectionRNA modificationsite-specific RNA cleavage

Identifiers

PMID34185947
PMCPMC8457104

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.