Evidence map›Paper›PMID 34185940›Full record

ArticleDepression and anxiety2021

Examining reciprocal associations between parent depressive symptoms and child internalizing symptoms on subsequent psychiatric disorders: An adoption study.

Camille C Cioffi, Leslie D Leve, Misaki N Natsuaki, Daniel S Shaw, David Reiss, Jody M Ganiban, Jenae M Neiderhiser

Open access · greenAbstract read
In one paragraph

Article in Depression and anxiety, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Parent-Child Neural Dynamics during a Stressful Task: Probing Associations with Temperament and Anxiety.Clinical psychological science : a journal of the Association for Psychological Science · 2026
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  10. Parenting in the Context of the Child: Genetic and Social Processes.Monographs of the Society for Research in Child Development · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Camille C CioffiPrevention Science Institute, University of Oregon, Eugene, Oregon, USA.ORCID 0000-0003-2424-7473
Leslie D LevePrevention Science Institute, University of Oregon, Eugene, Oregon, USA.ORCID 0000-0003-3061-4524
Misaki N NatsuakiDepartment of Psychology, University of California, Riverside, California, USA.ORCID 0000-0001-5585-7827
Daniel S ShawDepartment of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
David ReissChild Study Center, Yale University, New Haven, Connecticut, USA.ORCID 0000-0002-7701-0480
Jody M GanibanDepartment of Psychology, George Washington University, Washington, USA.ORCID 0000-0001-5908-6644
Jenae M NeiderhiserDepartment of Psychology, The Pennsylvania State University, Pennsylvania, USA.
University of Oregon · USGeorge Washington University · USPennsylvania State University · USUniversity of California, Riverside · USUniversity of Pittsburgh · USYale University · US

Funding

Supplement to Prevention Research Center: Parenting Among Women Who Are Opioid Users, Project 2P50DA048756 · NIDA · UNIVERSITY OF OREGON · PI MACKIEWICZ SEGHETE, KRISTEN L · 2019 to 2023
$18.0M
The Early Growth and Development Study Pediatric CohortUH3OD023389 · OD · UNIVERSITY OF OREGON · PI Jody M. Ganiban, Leslie Diane Leve · 2018 to 2026
$16.6M
The Early Growth and Development Study: Family Process, Genes and School EntryR01HD042608 · NICHD · OREGON SOCIAL LEARNING CENTER, INC. · PI CAPALDI, DEBORAH M. · 2002 to 2011
$14.9M
Genes, Prenatal Drug Exposure, and the Postnatal Environment: An Adoption StudyR01DA020585 · NIDA · PENNSYLVANIA STATE UNIVERSITY, THE · PI NEIDERHISER, JENAE M. · 2007 to 2011
$5.9M
An adoption study of the development of early substance use: the joint roles of genetic influences, prenatal risk, rearing environment, and pubertal maturationR01DA045108 · NIDA · PENNSYLVANIA STATE UNIVERSITY, THE · PI NEIDERHISER, JENAE M. · 2018 to 2022
$3.7M
Gene-Environment Interplay and Development of Psychiatric Symptoms in ChildrenR01MH092118 · NIMH · PENNSYLVANIA STATE UNIVERSITY, THE · PI LEVE, LESLIE DIANE, NEIDERHISER, JENAE M. · 2010 to 2014
$3.1M
Gene-Environment interplay and childhood obesity: An Adoption study.R01DK090264 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI GANIBAN, JODY M. · 2011 to 2015
$2.8M
Siblings Reared Apart: A Naturalistic Cross-Fostering Study of Young ChildrenR01DA035062 · NIDA · UNIVERSITY OF OREGON · PI LEVE, LESLIE DIANE · 2013 to 2016
$2.7M
Family and Peer Processes and G-E Interplay in Middle School: An Adoption StudyR56HD042608 · NICHD · UNIVERSITY OF OREGON · PI LEVE, LESLIE DIANE · 2014 to 2015
$700k
NICHD NIH HHS R01 HD042608NICHD NIH HHS R56 HD042608NIDA NIH HHS P50 DA048756NIDA NIH HHS R01 DA020585NIDA NIH HHS R01 DA035062NIDA NIH HHS R01 DA045108NIDDK NIH HHS R01 DK090264NIH HHS UH3 OD023389NIMH NIH HHS R01 MH092118
6 · The paper itself

Abstract

introductionThe dynamic interplay between parent depressive symptoms and child internalizing behavior over time is not well understood.

methodsWe used data from a prospective parent-offspring adoption design (N = 561) to examine associations between adoptive parent depressive symptoms and child internalizing behavior when children were ages 18 months, 27 months, 4.5 years, and 6 years, and subsequent child psychiatric disorder symptoms when children were between the ages of 6-8 years. Models also accounted for the contributions of birth parent psychopathology, birth mother depressive symptoms during pregnancy, and infant negative emotionality. Bidirectional associations between adoptive parent depressive symptoms and child internalizing behavior were examined using a random-intercept cross-lagged panel model.

resultsThere was evidence for associations between child internalizing behavior and adoptive parent depressive symptoms over time, with mothers' depressive symptoms being a more salient risk factor for child internalizing behavior than fathers'. We found one significant cross-lagged association from adoptive mother depressive symptoms at child age 18 months to child internalizing behavior at age 27 months. Infant negative emotionality (i.e., emotional liability) at age 9 months predicted both child internalizing behavior and adoptive parent depressive symptoms.

conclusionResults suggest that postnatal maternal depressive symptoms confer specific risks for child internalizing behaviors in toddlerhood and childhood and depressive symptoms in childhood.

Indexed as

Child Behavior DisordersDepressionChildFemaleHumansInfantMothersParentsPregnancyProspective Studieschild behaviordepressionparentsprospective studiespsychopathologyrisk factors

Identifiers

PMID34185940
PMCPMC8664963
OpenAlexW3176961280

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.