Evidence map›Paper›PMID 34185846›Full record

ReviewJournal of athletic training2022

An Evidence-Based Review of the Pathophysiology, Treatment, and Prevention of Exercise-Associated Muscle Cramps.

Kevin C Miller, Brendon P McDermott, Susan W Yeargin, Aidan Fiol, Martin P Schwellnus

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in Journal of athletic training, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07262879 (Effect of Nurse-Led Intradialytic Stretching Exercises on Muscle Cramp Burden Among Patients Undergoing Maintenance Hemodialysis), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07262879 nacompletednot on this mapstarted 2024, after this paper: background citation

Effect of Nurse-Led Intradialytic Stretching Exercises on Muscle Cramp Burden Among Patients Undergoing Maintenance Hemodialysis: A Randomized Controlled Trial

TypeinterventionalSponsorBeni-Suef UniversityRan2024 to 2025Enrolled60ConditionsMuscle Cramp, Renal Dialysis, Exercise Therapy, Nursing CareArmsNurse-Led Intradialytic Stretching Exercises
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  9. A review of nutritional recommendations for scuba divers.Journal of the International Society of Sports Nutrition · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Kevin C MillerSchool of Rehabilitation and Medical Sciences, Central Michigan University, Mount Pleasant.
Brendon P McDermottDepartment of Health, Human Performance and Recreation, University of Arkansas, Fayetteville.
Susan W YearginExercise Science Department, University of South Carolina, Columbia.
Aidan FiolDepartment of Health, Human Performance and Recreation, University of Arkansas, Fayetteville.
Martin P SchwellnusInstitute for Sport, Exercise Medicine and Lifestyle Research, University of Pretoria, South Africa.
University of Arkansas at Fayetteville · USCentral Michigan University · USUniversity of Pretoria · ZAUniversity of South Carolina · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exercise-associated muscle cramps (EAMCs) are common and frustrating for athletes and the physically active. We critically appraised the EAMC literature to provide evidence-based treatment and prevention recommendations. Although the pathophysiology of EAMCs appears controversial, recent evidence suggests that EAMCs are due to a confluence of unique intrinsic and extrinsic factors rather than a singular cause. The treatment of acute EAMCs continues to include self-applied or clinician-guided gentle static stretching until symptoms abate. Once the painful EAMCs are alleviated, the clinician can continue treatment on the sidelines by focusing on patient-specific risk factors that may have contributed to the onset of EAMCs. For EAMC prevention, clinicians should obtain a thorough medical history and then identify any unique risk factors. Individualizing EAMC prevention strategies will likely be more effective than generalized advice (eg, drink more fluids).

Indexed as

Muscle CrampMuscle Stretching ExercisesAthletesHumansRisk Factorsbest practicedehydrationelectrolytesfatiguerisk factors

Identifiers

PMID34185846
PMCPMC8775277
OpenAlexW3176976526

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.