ArticleHuman vaccines & immunotherapeutics2021
Is 'original antigenic sin' complicating indian vaccination drive against Covid-19?
Article in Human vaccines & immunotherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Parental Willingness and Factors Influencing COVID-19 Vaccination for Children in Saudi Arabia.Pediatric health, medicine and therapeutics · 2024Article
- Seasonal coronaviruses and SARS-CoV-2: effects of preexisting immunity during the COVID-19 pandemic.Journal of Zhejiang University. Science. B · 2022Article
- SARS-CoV-2 Spike Protein Vaccine-Induced Immune Imprinting Reduces Nucleocapsid Protein Antibody Response in SARS-CoV-2 Infection.Journal of immunology research · 2022Article
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Abstract
India is in the grip of a devastating second wave of Covid-19. Many experts believe new variants of concern (VOC) are behind this unprecedented surge. Some media reports are hinting toward higher risk of Covid infection following Covid vaccinations. 'Original antigenic sin,' in which a prior exposure to an antigen leads to an ineffective response to a related antigen, may offer one immunological explanation for this unusual association. There is an urgent need of undertaking a detailed study to prove/disprove this association.
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