Evidence map›Paper›PMID 34185572›Full record

GuidelineJCO global oncology2021

NGS in Lung, Breast, and Unknown Primary Cancer in Colombia: A Multidisciplinary Consensus on Challenges and Opportunities.

William Armando Mantilla, María Carolina Sanabria-Salas, Ana Margarita Baldion, Luz F Sua, Diego Mauricio Gonzalez, Mauricio Lema

Open access · goldAbstract readPractice GuidelineReview
In one paragraph

Guideline in JCO global oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Current patterns of next-generation sequencing testing in biliary tract cancer patients in Spain.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

William Armando MantillaFundacion Cardioinfantil, Universidad del Rosario, Bogotá, Colombia.ORCID 0000-0002-2778-164X
María Carolina Sanabria-SalasInstituto Nacional de Cancerología, Bogotá, Colombia.ORCID 0000-0002-7946-2026
Ana Margarita BaldionHead of the Pathology Section, Department of Pathology and Laboratory Medicine, Hospital Universitario Fundacion Santa Fe de Bogota, Bogotá, Colombia.
Luz F SuaDepartment of Pathology and Laboratory Medicine, Fundación Valle del Lili, and Faculty of Health Sciences, Universidad ICESI, Cali, Colombia.ORCID 0000-0001-9574-2370
Diego Mauricio GonzalezInstituto de Cancerología Las Americas-AUNA, Universidad de Antioquia, Antioquia, Colombia.ORCID 0000-0003-0907-7197
Mauricio LemaClínica de Oncología Astorga, Medellín, Colombia.ORCID 0000-0001-9346-0361
Fundación Santa Fe de Bogotá · COFundación Valle del Lili · COInstituto Nacional de Cancerología · COUniversidad de Antioquia · COUniversidad del Rosario · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the benefits and likely future applications, there is an urgent need to expand the use of next-generation sequencing (NGS) in breast, lung, and unknown primary cancers in Colombia. The objective of this review is to address the barriers limiting access to the use of NGS in Colombia, specifically for patients with breast, lung, and unknown primary cancers in the public health care system. A selected Panel of Colombian experts in NGS were provided with a series of relevant questions to address in a multiday conference. Each narrative was discussed and edited by the Panel through numerous drafts and rounds of discussion until consensus was achieved. There are limitations to the widespread adoption of innovative technology inherent to the Colombian health care system. Barriers identified to implementing NGS in Colombia include availability, accessibility, and affordability; limited infrastructure; training and awareness of health personnel; quality-control procedures; and collection of local data. Stakeholders must align to adapt the implementation of NGS to the constraints of resource-limited environments. Diagnostic algorithms were developed to guide molecular testing for lung, breast, and unknown primary cancers. Recommendations on overcoming the barriers to the widespread adoption of NGS include country-specific molecular testing guidelines, creating a national genetic registry, improving infrastructure, and creating health policy that favors the adoption of innovative technology.

Indexed as

Neoplasms, Unknown PrimaryColombiaConsensusHigh-Throughput Nucleotide SequencingHumansLung

Identifiers

PMID34185572
PMCPMC8457807
OpenAlexW3177142074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.