Evidence map›Paper›PMID 34185371›Full record

ArticleAngewandte Chemie (International ed. in English)2021

Molecular Plumbing to Bend Self-Assembling Peptide Nanotubes.

Federica Novelli, Marcos Vilela, Antía Pazó, Manuel Amorín, Juan R Granja

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Light-Triggered Disassembly of Peptide Nanostructures.Chembiochem : a European journal of chemical biology · 2025
    Article
  2. Article
  3. Article
  4. Molecular Plumbing to Bend Self-Assembling Peptide Nanotubes.Angewandte Chemie (International ed. in English) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Federica NovelliCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS) and Organic Chemistry Department, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain.ORCID 0000-0003-0902-9953
Marcos VilelaCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS) and Organic Chemistry Department, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain.ORCID 0000-0001-6459-2197
Antía PazóCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS) and Organic Chemistry Department, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain.
Manuel AmorínCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS) and Organic Chemistry Department, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain.ORCID 0000-0002-2992-5555
Juan R GranjaCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS) and Organic Chemistry Department, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain.ORCID 0000-0002-5842-7504

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Light-induced molecular piping of cyclic peptide nanotubes to form bent tubular structures is described. The process is based on the [4+4] photocycloaddition of anthracene moieties, whose structural changes derived from the interdigitated flat disposition of precursors to the corresponding cycloadduct moieties, induced the geometrical modifications in nanotubes packing that provokes their curvature. For this purpose, we designed a new class of cyclic peptide nanotubes formed by β- and α-amino acids. The presence of the former predisposes the peptide to stack in a parallel fashion with the β-residues aligned along the nanotube and the homogeneous distribution of anthracene pendants.

Indexed as

cyclic peptidesmolecular plumbingnanotubesphotodimerizationself-assembly

Identifiers

PMID34185371
PMCPMC8456905

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.