Evidence map›Paper›PMID 34185300›Full record

ReviewAdvances in experimental medicine and biology2020

Tumor Microenvironment in Penile Cancer.

Matthias Walter

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Matthias WalterDepartment of Urology, University Hospital Basel, University of Basel, Spitalstrasse 21, 4031, Basel, Switzerland. matthias.walter@usb.ch.
University Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Penile cancer is rare but associated with a high morbidity and mortality once metastasized. Besides presenting a fundamental overview of penile cancer, the current literature on key players associated with the pathogenesis of penile cancer including common labor chemistry parameters [neutrophil to lymphocyte ratio (NLR) and C-reactive protein CrP)], programmed cell death 1 (PD1)/PD ligand 1 (PD-L1), regulatory T cells (Tregs), forkhead box protein 3 (FoxP3, also known as scurfin), Ki-67 (also known as MKI67), protein 53 (p53), and pericytes has been reviewed and summarized. Furthermore, future directions and an overview of ongoing clinical trials are provided to highlight potential avenues that could improve cancer-specific and overall survival.

Indexed as

Penile NeoplasmsB7-H1 AntigenHumansMaleT-Lymphocytes, RegulatoryTumor MicroenvironmentB7-H1 AntigenC-reactive proteinCytotoxic T lymphocyte-associated protein 4Epidermal growth factor receptorFoxP3Human papilloma virusKi-67Neutrophil to lymphocyte ratioP53PD ligand 1PericytesProgrammed cell death 1Regulatory T cellsSquamous cell carcinomaTumor microenvironmentVascular endothelial growth factor

Identifiers

PMID34185300
OpenAlexW3176272433

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.