Evidence map›Paper›PMID 34185251›Full record

ReviewAmbio2022

The potential effects of microplastics on human health: What is known and what is unknown.

Kirsty Blackburn, Dannielle Green

Open access · greenAbstract readReview
In one paragraph

Review in Ambio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 2 pooled it
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 2 syntheses or guidelines pooled it, 423 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Article
  7. Article
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  12. Article
  13. The role of ultra-processed food in obesity.Nature reviews. Endocrinology · 2025
    Review
  14. Review
  15. Article
  16. Review
  17. Assessing inhalation intake of microplastics using MPPD model.Environmental analysis, health and toxicology · 2025
    Article
  18. Article
  19. Review
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Kirsty BlackburnApplied Ecology Research Group, School of Life Sciences, Anglia Ruskin University, Room 302 Science Centre, Cambridge, CB1 1PT, UK. kirstyjblackburn@gmail.com.ORCID http://orcid.org/0000-0002-6735-6189
Dannielle GreenApplied Ecology Research Group, School of Life Sciences, Anglia Ruskin University, Room 302 Science Centre, Cambridge, CB1 1PT, UK.
Anglia Ruskin University · GBWellcome Sanger Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microplastic contamination is ubiquitous in aquatic and terrestrial environments, found in water, sediments, within organisms and in the atmosphere and the biological effects on animal and plant life have been extensively investigated in recent years. There is growing evidence that humans are exposed to microplastics via ingestion of food and drink and through inhalation. Despite the prevalence of contamination, there has been limited research on the effects of microplastics on human health and most studies, to date, analyse the effects on model organisms with the likely impacts on human health being inferred by extrapolation. This review summarises the latest findings in the field with respect to the prevalence of microplastics in the human-environment, to what extent they might enter and persist in the body, and what effect, if any, they are likely to have on human health. Whilst definitive evidence linking microplastic consumption to human health is currently lacking, results from correlative studies in people exposed to high concentrations of microplastics, model animal and cell culture experiments, suggest that effects of microplastics could include provoking immune and stress responses and inducing reproductive and developmental toxicity. Further research is required to explore the potential implications of this recent contaminant in our environment in more rigorous clinical studies.

Indexed as

MicroplasticsWater Pollutants, ChemicalAnimalsEnvironmental MonitoringHumansPlasticsMicroplasticsPlasticsWater Pollutants, ChemicalHuman health risksIngestionInhalationMicroplasticsPOPs

Identifiers

PMID34185251
PMCPMC8800959
OpenAlexW3174766837

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.