Evidence map›Paper›PMID 34185240›Full record

ArticleScience China. Life sciences2022

Early changes to the extracellular space in the hippocampus under simulated microgravity conditions.

Yajuan Gao, Hongbin Han, Jichen Du, Qingyuan He, Yanxing Jia, Junhao Yan, Hui Dai, Bin Cui, Jing Yang, Xunbin Wei and 6 more

Abstract read
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In one paragraph

Article in Science China. Life sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Resistance and Aerobic Preconditioning Delays Unloading-Induced Multisystemic Physiological Changes: The NEBULA Project.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Yajuan GaoDepartment of Radiology, Peking University Third Hospital, Beijing, 100191, China.
Hongbin HanDepartment of Radiology, Peking University Third Hospital, Beijing, 100191, China. hanhongbin@bjmu.edu.cn.
Jichen DuBeijing Key Laboratory of Magnetic Resonance Imaging Technology, Beijing, 100191, China.
Qingyuan HeDepartment of Radiology, Peking University Third Hospital, Beijing, 100191, China.
Yanxing JiaState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Junhao YanDepartment of Anatomy and Histology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China.
Hui DaiNHC Key Laboratory of Medical Immunology, Department of Immunology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China.
Bin CuiDepartment of Radiology, Aerospace Center Hospital, Peking University Aerospace Clinical College, Beijing, 100039, China.
Jing YangDepartment of Neurology, Aerospace Center Hospital, Peking University Aerospace Clinical College, Beijing, 100039, China.
Xunbin WeiInstitute of Medical Technology, Peking University Health Science Center, Beijing, 100191, China.
Liu YangDepartment of Radiology, Peking University Third Hospital, Beijing, 100191, China.
Rui WangDepartment of Radiology, Peking University Third Hospital, Beijing, 100191, China.
Ren LongDepartment of Radiology, Peking University Third Hospital, Beijing, 100191, China.
Qiushi RenInstitute of Medical Technology, Peking University Health Science Center, Beijing, 100191, China.
Xing YangInstitute of Medical Technology, Peking University Health Science Center, Beijing, 100191, China.
Jiabin LuDepartment of Radiology, Peking University Third Hospital, Beijing, 100191, China.
Peking University · CNPeking University Third Hospital · CNAerospace Center Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The smooth transportation of substances through the brain extracellular space (ECS) is crucial to maintaining brain function; however, the way this occurs under simulated microgravity remains unclear. In this study, tracer-based magnetic resonance imaging (MRI) and D

Indexed as

Weightlessness SimulationAnimalsExtracellular FluidExtracellular SpaceHippocampusMagnetic Resonance ImagingMaleRatsRats, Sprague-Dawleybrain extracellular spacehindlimb-unloadinginterstitial fluidinterstitial systemsimulated microgravitytracer-based magnetic resonance imaging

Identifiers

PMID34185240
OpenAlexW3173843606

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.