Evidence map›Paper›PMID 34185234›Full record

ArticleJournal of autism and developmental disorders2022

Parental Language Input Predicts Neuroscillatory Patterns Associated with Language Development in Toddlers at Risk of Autism.

Rachel R Romeo, Boin Choi, Laurel J Gabard-Durnam, Carol L Wilkinson, April R Levin, Meredith L Rowe, Helen Tager-Flusberg, Charles A Nelson

Open access · greenAbstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 44 citations in OpenAlex.

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  19. Socioeconomic status and reading outcomes: Neurobiological and behavioral correlates.New directions for child and adolescent development · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rachel R RomeoDivision of Developmental Medicine, Boston Children's Hospital, Harvard Medical School, 1 Autumn Street, Boston, MA, 02215, USA. rachel.romeo@childrens.harvard.edu.ORCID http://orcid.org/0000-0002-0315-4385
Boin ChoiDivision of Developmental Medicine, Boston Children's Hospital, Harvard Medical School, 1 Autumn Street, Boston, MA, 02215, USA.
Laurel J Gabard-DurnamDivision of Developmental Medicine, Boston Children's Hospital, Harvard Medical School, 1 Autumn Street, Boston, MA, 02215, USA.
Carol L WilkinsonDivision of Developmental Medicine, Boston Children's Hospital, Harvard Medical School, 1 Autumn Street, Boston, MA, 02215, USA.
April R LevinDepartment of Neurology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA, 02215, USA.
Meredith L RoweHarvard Graduate School of Education, 13 Appian Way, Cambridge, MA, 02138, USA.
Helen Tager-FlusbergDepartment of Psychological and Brain Sciences, Boston University, 64 Cummington Mall, Boston, MA, 02215, USA.
Charles A NelsonDivision of Developmental Medicine, Boston Children's Hospital, Harvard Medical School, 1 Autumn Street, Boston, MA, 02215, USA.
Boston Children's Hospital · USBoston University · US

Funding

Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI Hisashi Umemori · 2021 to 2026
$9.4M
Neurobehavioral Research on Infants at Risk for SLI and AutismR01DC010290 · NIDCD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI NELSON, CHARLES ALEXANDER, TAGER-FLUSBERG, HELEN · 2009 to 2020
$7.5M
Translational Post-doctoral Training in NeurodevelopmentT32MH112510 · NIMH · BOSTON CHILDREN'S HOSPITAL · PI DAVID C GLAHN, CHARLES Alexander NELSON · 2017 to 2026
$2.6M
Infants at Risk for Autism Spectrum Disorders or Language DelayR21DC008637 · NIDCD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI TAGER-FLUSBERG, HELEN B. · 2006 to 2007
$439k
Autism Speaks 1323NICHD NIH HHS P50 HD105351NIDCD NIH HHS R01 DC010290NIDCD NIH HHS R01-DC010290NIDCD NIH HHS R21 DC008637NIDCD NIH HHS R21-DC08637NIMH NIH HHS T32 MH112510NIMH NIH HHS T32MH112510Simons Foundation 137186
6 · The paper itself

Abstract

In this study we investigated the impact of parental language input on language development and associated neuroscillatory patterns in toddlers at risk of Autism Spectrum Disorder (ASD). Forty-six mother-toddler dyads at either high (n = 22) or low (n = 24) familial risk of ASD completed a longitudinal, prospective study including free-play, resting electroencephalography, and standardized language assessments. Input quantity/quality at 18 months positively predicted expressive language at 24 months, and relationships were stronger for high-risk toddlers. Moderated mediations revealed that input-language relationships were explained by 24-month frontal and temporal gamma power (30-50 Hz) for high-risk toddlers who would later develop ASD. Results suggest that high-risk toddlers may be cognitively and neurally more sensitive to their language environments, which has implications for early intervention.

Indexed as

Autism Spectrum DisorderAutistic DisorderChild, PreschoolHumansInfantLanguage DevelopmentParentsProspective StudiesAutismEarly experienceEEGLanguage developmentLanguage input

Identifiers

PMID34185234
PMCPMC9594983
OpenAlexW3176031780

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.